Nickel-catalyzed asymmetric transfer hydrogenation of hydrazones and other ketimines

Haiyan Xu; Peng Yang; Pratanphorn Chuanprasit; Hajime Hirao; Jianrong Zhou

doi:10.1002/anie.201501018

Nickel-catalyzed asymmetric transfer hydrogenation of hydrazones and other ketimines

Haiyan Xu
, Peng Yang
, Pratanphorn Chuanprasit
, Hajime Hirao^*
, Jianrong Zhou^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

149 Citations (Scopus)

Abstract

We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak interactions may be important for stereochemical control by the nickel/binapine catalyst.

Original language	English
Pages (from-to)	5112-5116
Journal	Angewandte Chemie - International Edition
Volume	54
Issue number	17
DOIs	https://doi.org/10.1002/anie.201501018
Publication status	Published - 20 Apr 2015
Externally published	Yes

Research Keywords

asymmetric catalysis
hydrazones
hydride insertion
nickel
transfer hydrogenation

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title = "Nickel-catalyzed asymmetric transfer hydrogenation of hydrazones and other ketimines",

abstract = "We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak interactions may be important for stereochemical control by the nickel/binapine catalyst.",

keywords = "asymmetric catalysis, hydrazones, hydride insertion, nickel, transfer hydrogenation",

author = "Haiyan Xu and Peng Yang and Pratanphorn Chuanprasit and Hajime Hirao and Jianrong Zhou",

year = "2015",

month = apr,

day = "20",

doi = "10.1002/anie.201501018",

language = "English",

volume = "54",

pages = "5112--5116",

journal = "Angewandte Chemie - International Edition",

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T1 - Nickel-catalyzed asymmetric transfer hydrogenation of hydrazones and other ketimines

AU - Xu, Haiyan

AU - Yang, Peng

AU - Chuanprasit, Pratanphorn

AU - Hirao, Hajime

AU - Zhou, Jianrong

PY - 2015/4/20

Y1 - 2015/4/20

N2 - We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak interactions may be important for stereochemical control by the nickel/binapine catalyst.

AB - We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak interactions may be important for stereochemical control by the nickel/binapine catalyst.

KW - asymmetric catalysis

KW - hydrazones

KW - hydride insertion

KW - nickel

KW - transfer hydrogenation

UR - https://www.scopus.com/pages/publications/84927771922

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84927771922&origin=recordpage

U2 - 10.1002/anie.201501018

DO - 10.1002/anie.201501018

M3 - RGC 21 - Publication in refereed journal

C2 - 25737093

SN - 1433-7851

VL - 54

SP - 5112

EP - 5116

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 17

ER -

Nickel-catalyzed asymmetric transfer hydrogenation of hydrazones and other ketimines

Abstract

Research Keywords

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