New ways to identify novel bacterial antigens for vaccine development

Abdolreza (Reza) Movahedi; David J. Hampson

doi:10.1016/j.vetmic.2008.02.011

New ways to identify novel bacterial antigens for vaccine development

Abdolreza (Reza) Movahedi, David J. Hampson^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 62 - Review of books or of software (or similar publications/items) › peer-review

20 Citations (Scopus)

Abstract

This article provides an overview of developments in approaches to identify novel bacterial components for use in recombinant subunit vaccines. In particular it describes the processes involved in "reverse vaccinology", and some associated complementary technologies such as proteomics that can be used in the identification of new and potentially useful vaccine antigens. Results obtained from the application of these new methods are forming a basis for a new generation of vaccines for use in the control of bacterial infections of humans and animals.

Original language	English
Pages (from-to)	1-13
Journal	Veterinary Microbiology
Volume	131
Issue number	1-2
Online published	10 Mar 2008
DOIs	https://doi.org/10.1016/j.vetmic.2008.02.011
Publication status	Published - 18 Sept 2008
Externally published	Yes

Research Keywords

Bacteria
Genomics
Proteomics
Reverse vaccinology
Vaccines

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10.1016/j.vetmic.2008.02.011

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title = "New ways to identify novel bacterial antigens for vaccine development",

abstract = "This article provides an overview of developments in approaches to identify novel bacterial components for use in recombinant subunit vaccines. In particular it describes the processes involved in {"}reverse vaccinology{"}, and some associated complementary technologies such as proteomics that can be used in the identification of new and potentially useful vaccine antigens. Results obtained from the application of these new methods are forming a basis for a new generation of vaccines for use in the control of bacterial infections of humans and animals. ",

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author = "Movahedi, {Abdolreza (Reza)} and Hampson, {David J.}",

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doi = "10.1016/j.vetmic.2008.02.011",

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T1 - New ways to identify novel bacterial antigens for vaccine development

AU - Movahedi, Abdolreza (Reza)

AU - Hampson, David J.

PY - 2008/9/18

Y1 - 2008/9/18

N2 - This article provides an overview of developments in approaches to identify novel bacterial components for use in recombinant subunit vaccines. In particular it describes the processes involved in "reverse vaccinology", and some associated complementary technologies such as proteomics that can be used in the identification of new and potentially useful vaccine antigens. Results obtained from the application of these new methods are forming a basis for a new generation of vaccines for use in the control of bacterial infections of humans and animals.

AB - This article provides an overview of developments in approaches to identify novel bacterial components for use in recombinant subunit vaccines. In particular it describes the processes involved in "reverse vaccinology", and some associated complementary technologies such as proteomics that can be used in the identification of new and potentially useful vaccine antigens. Results obtained from the application of these new methods are forming a basis for a new generation of vaccines for use in the control of bacterial infections of humans and animals.

KW - Bacteria

KW - Genomics

KW - Proteomics

KW - Reverse vaccinology

KW - Vaccines

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-48849091840&origin=recordpage

U2 - 10.1016/j.vetmic.2008.02.011

DO - 10.1016/j.vetmic.2008.02.011

M3 - RGC 62 - Review of books or of software (or similar publications/items)

C2 - 18372122

SN - 0378-1135

VL - 131

SP - 1

EP - 13

JO - Veterinary Microbiology

JF - Veterinary Microbiology

IS - 1-2

ER -

New ways to identify novel bacterial antigens for vaccine development

Abstract

Research Keywords

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