New synthetic strategy for chiral 2-oxazolidinones derivatives via rhodium-catalyzed asymmetric hydrogenation

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)658-662
Journal / PublicationTetrahedron Letters
Volume57
Issue number6
Publication statusPublished - 10 Feb 2016
Externally publishedYes

Abstract

Asymmetric hydrogenation of 4-substituted cyclic enamido esters catalyzed by a rhodium-TangPhos complex provides an efficient method for the synthesis of chiral 4-substituted oxazolinones with excellent yields and good enantioselectivities. The products are valuable chiral building blocks and the applications as chiral auxiliaries and pharmaceuticals are well-known.

Research Area(s)

  • Asymmetric hydrogenation, Chiral 2-oxazolidinones, Enantioselectivity, Phosphine ligand, Rh-catalyzed

Bibliographic Note

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Citation Format(s)

New synthetic strategy for chiral 2-oxazolidinones derivatives via rhodium-catalyzed asymmetric hydrogenation. / Wang, Qingli; Tan, Xuefeng; Zhu, Ziyue et al.
In: Tetrahedron Letters, Vol. 57, No. 6, 10.02.2016, p. 658-662.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review