Abstract
Autophagy is a highly conserved biological process in eukaryotes, which degrades cellular misfolded proteins, damaged organelles and invasive pathogens in the lysosome-dependent manner. Autoimmune diseases caused by genetic elements, environments and aberrant immune responses severely impact patients’ living quality and even threaten life. Recently, numerous studies have reported autophagy can regulate immune responses, and play an important role in autoimmune diseases. In this review, we summarised the features of autophagy and autophagy-related genes, enumerated some autophagy-related genes involved in autoimmune diseases, and further overviewed how to treat autoimmune diseases through targeting autophagy. Finally, we outlooked the prospect of relieving and curing autoimmune diseases by targeting autophagy pathway. © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
| Original language | English |
|---|---|
| Article number | 2351872 |
| Journal | Autoimmunity |
| Volume | 57 |
| Issue number | 1 |
| Online published | 13 May 2024 |
| DOIs | |
| Publication status | Published - 2024 |
Research Keywords
- ATGs
- Autoimmune diseases
- autophagy
- treatments strategies
Publisher's Copyright Statement
- This full text is made available under CC-BY-NC 4.0. https://creativecommons.org/licenses/by-nc/4.0/
Fingerprint
Dive into the research topics of 'New insight in treating autoimmune diseases by targeting autophagy'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver