New forms of superparamagnetic nanoparticles for biomedical applications

Chenjie Xu; Shouheng Sun

doi:10.1016/j.addr.2012.10.008

New forms of superparamagnetic nanoparticles for biomedical applications

Chenjie Xu^*, Shouheng Sun^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

345 Citations (Scopus)

Abstract

Magnetic nanoparticles (MNPs) based on iron oxide, especially magnetite (Fe₃O₄), have been explored as sensitive probes for magnetic resonance imaging and therapeutic applications. Such application potentials plus the need to achieve high efficiency and sensitivity have motivated the search for new forms of superparamagnetic NPs with additional chemical and physical functionalities. This review summarizes the latest development of high moment MNPs, multifunctional MNPs, and porous hollow MNPs for biosensing, molecular imaging, and drug delivery applications. © 2012 Elsevier B.V.

Original language	English
Pages (from-to)	732-743
Journal	Advanced Drug Delivery Reviews
Volume	65
Issue number	5
Online published	2 Nov 2012
DOIs	https://doi.org/10.1016/j.addr.2012.10.008
Publication status	Published - May 2013
Externally published	Yes

Research Keywords

Biomedical application
Drug delivery
Magnetic nanoparticles
Modification
Molecular imaging
Synthesis

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abstract = "Magnetic nanoparticles (MNPs) based on iron oxide, especially magnetite (Fe3O4), have been explored as sensitive probes for magnetic resonance imaging and therapeutic applications. Such application potentials plus the need to achieve high efficiency and sensitivity have motivated the search for new forms of superparamagnetic NPs with additional chemical and physical functionalities. This review summarizes the latest development of high moment MNPs, multifunctional MNPs, and porous hollow MNPs for biosensing, molecular imaging, and drug delivery applications. {\textcopyright} 2012 Elsevier B.V.",

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T1 - New forms of superparamagnetic nanoparticles for biomedical applications

AU - Xu, Chenjie

AU - Sun, Shouheng

PY - 2013/5

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N2 - Magnetic nanoparticles (MNPs) based on iron oxide, especially magnetite (Fe3O4), have been explored as sensitive probes for magnetic resonance imaging and therapeutic applications. Such application potentials plus the need to achieve high efficiency and sensitivity have motivated the search for new forms of superparamagnetic NPs with additional chemical and physical functionalities. This review summarizes the latest development of high moment MNPs, multifunctional MNPs, and porous hollow MNPs for biosensing, molecular imaging, and drug delivery applications. © 2012 Elsevier B.V.

AB - Magnetic nanoparticles (MNPs) based on iron oxide, especially magnetite (Fe3O4), have been explored as sensitive probes for magnetic resonance imaging and therapeutic applications. Such application potentials plus the need to achieve high efficiency and sensitivity have motivated the search for new forms of superparamagnetic NPs with additional chemical and physical functionalities. This review summarizes the latest development of high moment MNPs, multifunctional MNPs, and porous hollow MNPs for biosensing, molecular imaging, and drug delivery applications. © 2012 Elsevier B.V.

KW - Biomedical application

KW - Drug delivery

KW - Magnetic nanoparticles

KW - Modification

KW - Molecular imaging

KW - Synthesis

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84878349852&origin=recordpage

U2 - 10.1016/j.addr.2012.10.008

DO - 10.1016/j.addr.2012.10.008

M3 - RGC 21 - Publication in refereed journal

C2 - 23123295

SN - 0169-409X

VL - 65

SP - 732

EP - 743

JO - Advanced Drug Delivery Reviews

JF - Advanced Drug Delivery Reviews

IS - 5

ER -

New forms of superparamagnetic nanoparticles for biomedical applications

Abstract

Research Keywords

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