Neuropeptide Y Gene × Environment Interaction Predicts Resilience and Positive Future Focus

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)438-458
Journal / PublicationApplied Psychology: Health and Well-Being
Volume11
Issue number3
Online published13 Jun 2019
Publication statusPublished - Nov 2019

Abstract

Background: The objective of this study was to investigate whether the NPY rs16147 polymorphism interacts with the environment to have an impact on resilience and positive future focus. Methods: In Study 1, 1,140 earthquake survivors were evaluated; self-reported trauma exposure level and resilience were reported. Study 2 included 2,370 company employees and university students; information regarding self-reported early stressful life events and positive future focus were obtained. Results: In both studies, the results showed a significant effect of interaction between the NPY rs16147 polymorphism and the level of stress on resilience. In Study 1, the T allele carriers reported consistent levels of resilience in low, moderate, and high levels of trauma exposure. In Study 2, the T genotype was associated with higher levels of positive future focus following early adversity. Conclusions: Our findings are discussed in light of the differential post-stress growth hypothesis.

Research Area(s)

  • differential post-stress growth hypothesis, G×E interaction, NPY rs16147 polymorphism, positive future focus, resilience

Bibliographic Note

Full text of this publication does not contain sufficient affiliation information. With consent from the author(s) concerned, the Research Unit(s) information for this record is based on the existing academic department affiliation of the author(s).