Multiple Stressor Effects of Radon and Phthalates in Children : Background Information and Future Research

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Detail(s)

Original languageEnglish
Article number2898
Journal / PublicationInternational Journal of Environmental Research and Public Health
Volume17
Issue number8
Online published22 Apr 2020
Publication statusPublished - Apr 2020

Link(s)

Abstract

The present paper reviews available background information for studying multiple stressor effects of radon (222 Rn) and phthalates in children and provides insights on future directions. In realistic situations, living organisms are collectively subjected to many environmental stressors, with the resultant effects being referred to as multiple stressor effects. Radon is a naturally occurring radioactive gas that can lead to lung cancers. On the other hand, phthalates are semi-volatile organic compounds widely applied as plasticizers to provide flexibility to plastic in consumer products. Links of phthalates to various health effects have been reported, including allergy and asthma. In the present review, the focus on indoor contaminants was due to their higher concentrations and to the higher indoor occupancy factor, while the focus on the pediatric population was due to their inherent sensitivity and their spending more time close to the floor. Two main future directions in studying multiple stressor effects of radon and phthalates in children were proposed. The first one was on computational modeling and micro-dosimetric studies, and the second one was on biological studies. In particular, dose-response relationship and effect-specific models for combined exposures to radon and phthalates would be necessary. The ideas and methodology behind such proposed research work are also applicable to studies on multiple stressor effects of collective exposures to other significant airborne contaminants, and to population groups other than children.

Research Area(s)

  • Children, Dosimetric modeling, Multiple stressor effects, Phthalates, Radon

Citation Format(s)

Multiple Stressor Effects of Radon and Phthalates in Children : Background Information and Future Research. / Kwan, W. S.; Nikezic, D.; Roy, Vellaisamy A. L.; Yu, K. N.

In: International Journal of Environmental Research and Public Health, Vol. 17, No. 8, 2898, 04.2020.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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