Multi-functional nanoparticles for cancer therapy

Dev Kumar Chatterjee; Yong Zhang

doi:10.1016/j.stam.2006.09.008

Multi-functional nanoparticles for cancer therapy

Dev Kumar Chatterjee
, Yong Zhang

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

21 Citations (Scopus)

Abstract

Many immunotherapeutic strategies developed in recent years involve the targeting of immune cells to tumors. In this study, we synthesized and characterized modified fluorescent nanoparticles as a targeting and delivery system, by conjugating both tumor targeting agent and chemokines to the nanoparticles, to attract immune cells to tumor cells. Biodegradable chitosan nanoparticles encapsulating quantum dots were prepared, with suitable surface modification to immobilize both tumor targeting agent and chemokine on their surfaces. The interactions between immune cells and tumor cells were visualized using optical microscope. © 2006 NIMS and Elsevier Ltd.

Original language	English
Pages (from-to)	131-133
Journal	Science and Technology of Advanced Materials
Volume	8
Issue number	1-2
DOIs	https://doi.org/10.1016/j.stam.2006.09.008
Publication status	Published - Jan 2007
Externally published	Yes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Keywords

Cancer
Chitosan
Immunotherapy
Nanomedicine
Nanoparticles
Quantum dots

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10.1016/j.stam.2006.09.008

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title = "Multi-functional nanoparticles for cancer therapy",

abstract = "Many immunotherapeutic strategies developed in recent years involve the targeting of immune cells to tumors. In this study, we synthesized and characterized modified fluorescent nanoparticles as a targeting and delivery system, by conjugating both tumor targeting agent and chemokines to the nanoparticles, to attract immune cells to tumor cells. Biodegradable chitosan nanoparticles encapsulating quantum dots were prepared, with suitable surface modification to immobilize both tumor targeting agent and chemokine on their surfaces. The interactions between immune cells and tumor cells were visualized using optical microscope. {\textcopyright} 2006 NIMS and Elsevier Ltd.",

keywords = "Cancer, Chitosan, Immunotherapy, Nanomedicine, Nanoparticles, Quantum dots",

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note = "Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected]. ",

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month = jan,

doi = "10.1016/j.stam.2006.09.008",

language = "English",

volume = "8",

pages = "131--133",

journal = "Science and Technology of Advanced Materials",

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publisher = "Taylor \& Francis",

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TY - JOUR

T1 - Multi-functional nanoparticles for cancer therapy

AU - Chatterjee, Dev Kumar

AU - Zhang, Yong

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2007/1

Y1 - 2007/1

N2 - Many immunotherapeutic strategies developed in recent years involve the targeting of immune cells to tumors. In this study, we synthesized and characterized modified fluorescent nanoparticles as a targeting and delivery system, by conjugating both tumor targeting agent and chemokines to the nanoparticles, to attract immune cells to tumor cells. Biodegradable chitosan nanoparticles encapsulating quantum dots were prepared, with suitable surface modification to immobilize both tumor targeting agent and chemokine on their surfaces. The interactions between immune cells and tumor cells were visualized using optical microscope. © 2006 NIMS and Elsevier Ltd.

AB - Many immunotherapeutic strategies developed in recent years involve the targeting of immune cells to tumors. In this study, we synthesized and characterized modified fluorescent nanoparticles as a targeting and delivery system, by conjugating both tumor targeting agent and chemokines to the nanoparticles, to attract immune cells to tumor cells. Biodegradable chitosan nanoparticles encapsulating quantum dots were prepared, with suitable surface modification to immobilize both tumor targeting agent and chemokine on their surfaces. The interactions between immune cells and tumor cells were visualized using optical microscope. © 2006 NIMS and Elsevier Ltd.

KW - Cancer

KW - Chitosan

KW - Immunotherapy

KW - Nanomedicine

KW - Nanoparticles

KW - Quantum dots

UR - https://www.scopus.com/pages/publications/33847257810

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-33847257810&origin=recordpage

U2 - 10.1016/j.stam.2006.09.008

DO - 10.1016/j.stam.2006.09.008

M3 - RGC 21 - Publication in refereed journal

SN - 1468-6996

VL - 8

SP - 131

EP - 133

JO - Science and Technology of Advanced Materials

JF - Science and Technology of Advanced Materials

IS - 1-2

ER -

Multi-functional nanoparticles for cancer therapy

Abstract

Bibliographical note

UN SDGs

Research Keywords

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