Abstract
Chitosan was used to encapsulate both CdSe/ZnS quantum dots (QDs) and the magnetic resonance imaging (MRI) contrast agent gadolinium- diethylenetriaminepentaacetate (Gd-DTPA), forming multi-functional nanoparticles that can be used in a wide range of in vitro or in vivo studies as fluorescent biological labels as well as MRI contrast agents, respectively. Multi-color QDs at pre-determined molar ratios were encapsulated into chitosan nanoparticles to produce bar-coding fluorescent labels. The encapsulated QDs and Gd-DTPA still maintained their desirable optical properties and relatively high relaxivity, respectively. The chitosan nanoparticles also showed good aqueous stability and enhanced biocompatibility on myoblast cells. Copyright © 2007 American Scientific Publishers All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 2389-2393 |
| Journal | Journal of Nanoscience and Nanotechnology |
| Volume | 7 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2007 |
| Externally published | Yes |
Bibliographical note
Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].Research Keywords
- Chitosan
- Fluorescent
- Gd-DTPA
- Magnetic
- Nanoparticle
- Quantum dot
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