Mono-PEGylated zinc(II) phthalocyanines: Preparation, nanoparticle formation, and in vitro photodynamic activity

Baozhong Zhao, Wubiao Duan, Pui-Chi Lo, Lei Duan, Chi Wu, Dennis K. P. Ng

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

26 Citations (Scopus)

Abstract

PEGged! A series of mono-PEGylated zinc(II) phthalocyanines for photodynamic therapy with singlet oxygen have been prepared and formulated in aqueous media with different methods. The system based on silica nanoparticles exhibits remarkably high stability and in vitro photocytotoxicity. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)55-59
JournalChemistry - An Asian Journal
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 2013
Externally publishedYes

Research Keywords

  • nanoparticles
  • photodynamic therapy
  • photosensitizers
  • phthalocyanines
  • polyethylene glycol

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