Abstract
Introduction: Previous studies have shown that the bactericidal performances of molybdenum disulfide (MoS2) were strongly related to the light-stimulated generation of reactive oxygen species (ROS)[1]. This work presented the synthesis and antibacterial actions of MoS2 nanosheets coated on titanium (Ti) substrate. The antibacterial mechanisms of MoS2 coatings were also studied.
Materials & Methods: MoS2 nanosheets were vertically aligned on the Ti substrate through a one-pot hydrothermal process. Different thicknesses of MoS2 coatings were achieved at the same time during this one-step preparation by diversifying the substrate placement: lying flatly and hanging vertically. Doping of iron was realized by adding EDTANaFe in the reactants.
Results & Discussion: The MoS2 coatings exhibited outstanding antibacterial activity against both Escherichia coli and Staphylococcus aureus in the dark (antibacterial efficiency: up to 100% after 24 hours). The releasing of MoO42- and light-independent formation of MoS2-induced ROS were demonstrated to account for the excellent antibacterial performances. Moreover, iron-dopings in terms of ferrous molybdate (FeMoO4) could accelerate the antibacterial process by releasing ferrous ions and boost the yield of ROS via a Fenton-like reaction series.
Conclusions: The bactericidal efficiency of the vertically aligned MoS2 nanosheets on the Ti substrate could be concluded to be the integrated results of ion release and ROS generation, which provided new references for the development and biomedical disinfection applications of MoS2 under dark conditions.
Materials & Methods: MoS2 nanosheets were vertically aligned on the Ti substrate through a one-pot hydrothermal process. Different thicknesses of MoS2 coatings were achieved at the same time during this one-step preparation by diversifying the substrate placement: lying flatly and hanging vertically. Doping of iron was realized by adding EDTANaFe in the reactants.
Results & Discussion: The MoS2 coatings exhibited outstanding antibacterial activity against both Escherichia coli and Staphylococcus aureus in the dark (antibacterial efficiency: up to 100% after 24 hours). The releasing of MoO42- and light-independent formation of MoS2-induced ROS were demonstrated to account for the excellent antibacterial performances. Moreover, iron-dopings in terms of ferrous molybdate (FeMoO4) could accelerate the antibacterial process by releasing ferrous ions and boost the yield of ROS via a Fenton-like reaction series.
Conclusions: The bactericidal efficiency of the vertically aligned MoS2 nanosheets on the Ti substrate could be concluded to be the integrated results of ion release and ROS generation, which provided new references for the development and biomedical disinfection applications of MoS2 under dark conditions.
| Original language | English |
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| Publication status | Published - Aug 2019 |
| Event | 2019 Chinese Biomaterials Congress & International Symposium on Advanced Biomaterials - Dalian World Expo Center, Dalian, China Duration: 22 Aug 2019 → 25 Aug 2019 http://2019congress.csbm.org.cn/ |
Conference
| Conference | 2019 Chinese Biomaterials Congress & International Symposium on Advanced Biomaterials |
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| Country/Territory | China |
| City | Dalian |
| Period | 22/08/19 → 25/08/19 |
| Internet address |
Bibliographical note
Research Unit(s) information for this publication is provided by the author(s) concerned.Research Keywords
- Molybdenum disulfide
- antibacterial activity
- iron
- reactive oxygen species
- titanium