Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

5 Scopus Citations
View graph of relations

Author(s)

  • Yanyan Zhang
  • Zhiwei Zheng
  • Edward Wai-Chi Chan
  • Ning Dong
  • Xiaodong Xia

Detail(s)

Original languageEnglish
Article numbere00529-18
Journal / PublicationAntimicrobial Agents and Chemotherapy
Volume62
Issue number7
Online published26 Jun 2018
Publication statusPublished - Jul 2018
Externally publishedYes

Abstract

This study reports the prevalences of qnrVC genes in 74 ciprofloxacin-resistant Vibrio sp. isolates. Two novel functional qnrVC alleles, qnrVC8 and qnrVC9, sharing 98% and 99% nucleotide similarity with qnrVC6 and qnrVC7, respectively, were identified. Our findings suggested that carriage of qnrVC alleles, together with target mutations in gyrA and parC genes, may contribute to the development of fluoroquinolone resistance in Vibrio species, posing a serious threat to public health.

Research Area(s)

  • Ciprofloxacin resistance, QnrVC, Vibrio

Citation Format(s)

Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China. / Zhang, Yanyan; Zheng, Zhiwei; Chan, Edward Wai-Chi; Dong, Ning; Xia, Xiaodong; Chen, Sheng.

In: Antimicrobial Agents and Chemotherapy, Vol. 62, No. 7, e00529-18, 07.2018.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal