Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China

Yanyan Zhang; Zhiwei Zheng; Edward Wai-Chi Chan; Ning Dong; Xiaodong Xia; Sheng Chen

doi:10.1128/AAC.00529-18

Author(s)

Yanyan Zhang
Zhiwei Zheng
Edward Wai-Chi Chan
Ning Dong
Xiaodong Xia

Detail(s)

Original language	English
Article number	e00529-18
Journal / Publication	Antimicrobial Agents and Chemotherapy
Volume	62
Issue number	7
Online published	26 Jun 2018
Publication status	Published - Jul 2018
Externally published	Yes

Link(s)

DOI	DOI https://doi.org/10.1128/AAC.00529-18 Final Published version
	Check@CityULib
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-85049000569&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(9be06a35-e4b4-4a0b-8e37-ffaf6ff94a3c).html

Abstract

This study reports the prevalences of qnrVC genes in 74 ciprofloxacin-resistant Vibrio sp. isolates. Two novel functional qnrVC alleles, qnrVC8 and qnrVC9, sharing 98% and 99% nucleotide similarity with qnrVC6 and qnrVC7, respectively, were identified. Our findings suggested that carriage of qnrVC alleles, together with target mutations in gyrA and parC genes, may contribute to the development of fluoroquinolone resistance in Vibrio species, posing a serious threat to public health.

Research Area(s)

Ciprofloxacin resistance, QnrVC, Vibrio

Citation Format(s)

[ RIS ] [ BibTeX ]

Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China. / Zhang, Yanyan; Zheng, Zhiwei; Chan, Edward Wai-Chi; Dong, Ning; Xia, Xiaodong; Chen, Sheng.

In: Antimicrobial Agents and Chemotherapy, Vol. 62, No. 7, e00529-18, 07.2018.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Zhang, Y, Zheng, Z, Chan, EW-C, Dong, N, Xia, X & Chen, S 2018, 'Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China', Antimicrobial Agents and Chemotherapy, vol. 62, no. 7, e00529-18. https://doi.org/10.1128/AAC.00529-18

Zhang, Y., Zheng, Z., Chan, E. W-C., Dong, N., Xia, X., & Chen, S. (2018). Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China. Antimicrobial Agents and Chemotherapy, 62(7), [e00529-18]. https://doi.org/10.1128/AAC.00529-18

Zhang Y, Zheng Z, Chan EW-C, Dong N, Xia X, Chen S. Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China. Antimicrobial Agents and Chemotherapy. 2018 Jul;62(7). e00529-18. https://doi.org/10.1128/AAC.00529-18

Zhang, Yanyan ; Zheng, Zhiwei ; Chan, Edward Wai-Chi ; Dong, Ning ; Xia, Xiaodong ; Chen, Sheng. / Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China. In: Antimicrobial Agents and Chemotherapy. 2018 ; Vol. 62, No. 7.