Modification of 1,2,4,5-tetrazine with cationic rhenium(i) polypyridine units to afford phosphorogenic bioorthogonal probes with enhanced reaction kinetics

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)3442-3445
Journal / PublicationChemical Communications
Volume51
Issue number16
Online published21 Jan 2015
Publication statusPublished - 25 Feb 2015

Abstract

New phosphorogenic bioorthogonal probes derived from mononuclear and binuclear rhenium(i) polypyridine complexes containing a 1,2,4,5-tetrazine moiety were designed; these complexes displayed substantial dienophile-induced emission enhancement, and accelerated reaction kinetics and could target a protein conjugate in living cells.

Citation Format(s)

Modification of 1,2,4,5-tetrazine with cationic rhenium(i) polypyridine units to afford phosphorogenic bioorthogonal probes with enhanced reaction kinetics. / Choi, Alex Wing-Tat; Tso, Karson Ka-Shun; Yim, Vicki Man-Wai; Liu, Hua-Wei; Lo, Kenneth Kam-Wing.

In: Chemical Communications, Vol. 51, No. 16, 25.02.2015, p. 3442-3445.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal