Abstract
Studying the Nasopharyngeal carcinoma (NPC) cell migration behavior in a three-dimensional (3D) platform could lead to a better understanding of NPC metastatic dissemination. In this work, a 3D platform with porous membrane and guiding grating patterns was developed. The orientation of the guiding grating relative to the trench direction in the bottom layer and the effects of trench size on cell traversing probability through porous membrane were investigated. More cells traversed through porous membrane with guiding grating perpendicular to the trench direction in the bottom layer. Probability of cell traversing porous membrane increased as the trench size increased from 10 to 30 μm and decreased when the trench was 70 μm wide with guiding grating perpendicular to trench direction.
| Original language | English |
|---|---|
| Publication status | Published - Sept 2017 |
| Event | 43rd International Conference on Micro and Nanoengineering (MNE2017) - Braga, Portugal Duration: 18 Sept 2017 → 22 Sept 2017 http://mne2017.org/about-mne-2017-novel-items/ http://mne2017.org/wp-content/uploads/2017/10/Booklet_MNE_FINAL_WEB.pdf (Conference Booklet) |
Conference
| Conference | 43rd International Conference on Micro and Nanoengineering (MNE2017) |
|---|---|
| Place | Portugal |
| City | Braga |
| Period | 18/09/17 → 22/09/17 |
| Internet address |
Bibliographical note
Research Unit(s) information for this record is provided by the author(s) concerned.UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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