Micropatterning of bioactive ligands for high-throughput study neuronal network functions

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review

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Author(s)

Detail(s)

Original languageEnglish
Title of host publicationProceedings of the IEEE Conference on Nanotechnology
Pages170-173
Publication statusPublished - 2013

Publication series

Name
ISSN (Print)1944-9399
ISSN (Electronic)1944-9380

Conference

Title13th IEEE International Conference on Nanotechnology (IEEE-NANO 2013)
LocationShangri-La Hotel
PlaceChina
CityBeijing
Period5 - 8 August 2013

Abstract

Synapses are essential components for signal processing and transmission in the nervous system, whose function is affected in many brain diseases and disorders. We demonstrated the successful control of synapse formation by micropatterning of synaptogenic protein, neuroligin (NL). Interestingly, the presence of a hydrophobic GPI moiety, promoted NL's biological activity. Also, the micropatterns of synaptogenic factors were included in a neurite growth/guidance platform, which could directly be used as a high-throughput platform for study different aspects in the development and dynamics of neuronal network. © 2013 IEEE.

Citation Format(s)

Micropatterning of bioactive ligands for high-throughput study neuronal network functions. / Li, Wei; Xu, Zhen; Shi, Peng.

Proceedings of the IEEE Conference on Nanotechnology. 2013. p. 170-173 6720879.

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review