Micro-optical coherence tomography tracking of magnetic gene transfection via Au-Fe3O4 dumbbell nanoparticles

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

18 Scopus Citations
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Author(s)

  • Wei Shi
  • Xinyu Liu
  • Chao Wei
  • Zhichuan J. Xu
  • Stanley Siong Wei Sim
  • Linbo Liu

Detail(s)

Original languageEnglish
Pages (from-to)17249-17253
Journal / PublicationNanoscale
Volume7
Issue number41
Online published23 Sep 2015
Publication statusPublished - 7 Nov 2015
Externally publishedYes

Abstract

Heterogeneous Au-Fe3O4 dumbbell nanoparticles (NPs) are composed of Au NPs and Fe3O4 NPs that bring in optical and magnetic properties respectively. This article reports the engineering of Au-Fe3O4 NPs as gene carriers for magnetic gene transfection as well as contrast agents for micro-optical coherence tomography (μOCT). As a proof-of-concept, Au-Fe3O4 NPs are used to deliver the green fluorescent protein to HEK 293T cells and their entrance into the cells is monitored through μOCT.

Citation Format(s)

Micro-optical coherence tomography tracking of magnetic gene transfection via Au-Fe3O4 dumbbell nanoparticles. / Shi, Wei; Liu, Xinyu; Wei, Chao; Xu, Zhichuan J.; Sim, Stanley Siong Wei; Liu, Linbo; Xu, Chenjie.

In: Nanoscale, Vol. 7, No. 41, 07.11.2015, p. 17249-17253.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review