TY - GEN
T1 - Microfluidic systems using localized molecular imprinting polymers for detection of nano-scale bio-molecules based on surface plasmon resonance
AU - Lee, Gwo-Bin
AU - Chen, Shean-Jen
AU - Huang, Shih-Chiang
AU - Chien, Fan-Ching
AU - Chen, Wen-Janq
N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].
PY - 2005
Y1 - 2005
N2 - This paper reports a new microfluidic system integrated with localized molecular imprinting polymers (MIP) for detection of nano-scale bio-molecules based on surface plasmon resonance (SPR). The label-free bio-sensing method incorporates SPR biosensing and an innovative microfluidic biochip capable of transporting a specific amount of bio-samples inside multiple microchannels using micropumps to sensing regions where multiple MIP films are locally spun-coated such that highly-sensitive, high-throughput, and highly-specific bio-sensing of nano-scale bio-molecules could be achieved. The microfluidic SPR/MIP biochips have the potential to be widely used for nano bio-sensing applications. While compared to large-scale SPR techniques, the developed microfluidic system has a comparable sensitivity with less consumption of samples and can perform the sensing in an automatic format. ©2005 IEEE.
AB - This paper reports a new microfluidic system integrated with localized molecular imprinting polymers (MIP) for detection of nano-scale bio-molecules based on surface plasmon resonance (SPR). The label-free bio-sensing method incorporates SPR biosensing and an innovative microfluidic biochip capable of transporting a specific amount of bio-samples inside multiple microchannels using micropumps to sensing regions where multiple MIP films are locally spun-coated such that highly-sensitive, high-throughput, and highly-specific bio-sensing of nano-scale bio-molecules could be achieved. The microfluidic SPR/MIP biochips have the potential to be widely used for nano bio-sensing applications. While compared to large-scale SPR techniques, the developed microfluidic system has a comparable sensitivity with less consumption of samples and can perform the sensing in an automatic format. ©2005 IEEE.
KW - Microfluidics
KW - Micropumps
KW - MIP
KW - SPR
UR - https://www.scopus.com/pages/publications/33746874126
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-33746874126&origin=recordpage
U2 - 10.1109/NANO.2005.1500664
DO - 10.1109/NANO.2005.1500664
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 0780391993
SN - 9780780391994
VL - 2
T3 - 2005 5th IEEE Conference on Nanotechnology
SP - 113
EP - 116
BT - 2005 5th IEEE Conference on Nanotechnology
T2 - 2005 5th IEEE Conference on Nanotechnology
Y2 - 11 July 2005 through 15 July 2005
ER -