Microfluidic microarray assembly and its applications to multi-sample DNA hybridization

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review

1 Scopus Citations
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Author(s)

  • Xing Yue Larry Peng
  • Lin Wang
  • Hua-Zhong Hogan Yu
  • Ash M. Parameswaran
  • Wa Lok Jacky Chou

Detail(s)

Original languageEnglish
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages823-825
Volume1
ISBN (Print)0974361119, 9780974361116
Publication statusPublished - 2005
Externally publishedYes

Publication series

NameMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume1

Conference

Title9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
PlaceUnited States
CityBoston, MA
Period9 - 13 October 2005

Abstract

A microfluidic microarray assembly (MMA) concept has been developed for multi-sample DNA hybridization. Both the creation of the microarray and the hybridization of DNA samples are achieved by microfluidic flow in microchannels without the robotic spotting procedure. By centrifugal force pumping in CD-like chips, 96 samples were tested simultaneously and the hybridization process could be performed in 3 minutes. The detection limit is down to one femtomole of oligonucleotide. Copyright © 2005 by the Transducer Research Foundation, Inc.

Research Area(s)

  • Centrifugal pumping, DNA microarray, Multi-sample DNA hybridization, Spiral microchannels

Bibliographic Note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to lbscholars@cityu.edu.hk.

Citation Format(s)

Microfluidic microarray assembly and its applications to multi-sample DNA hybridization. / Peng, Xing Yue Larry; Li, Paul C.H.; Wang, Lin; Yu, Hua-Zhong Hogan; Parameswaran, Ash M.; Chou, Wa Lok Jacky.

Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Vol. 1 Transducer Research Foundation, 2005. p. 823-825 (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences; Vol. 1).

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review