Microfluidic devices for circulating tumor cells isolation and subsequent analysis
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
| Original language | English |
|---|---|
| Pages (from-to) | 810-821 |
| Journal / Publication | Current Pharmaceutical Biotechnology |
| Volume | 17 |
| Issue number | 9 |
| Publication status | Published - 1 Jul 2016 |
| Externally published | Yes |
Link(s)
Abstract
The research of circulating tumor cells (CTCs) has drawn much attention in recent years. It is because of the potential values of CTCs in early diagnosis of cancer, management of clinical treatment, exploration of metastatic mechanism, and development of personalized medicine. However, isolating CTCs has been technically challenging due to their rare numbers in blood. Recently, a variety of microfluidic devices have been developed for CTC isolation, and these devices can realize high capture efficiency and high purity. While enumeration of CTCs has been achieved, further cellular and DNA analysis on the captured CTCs are less reported. In this article, we review recent reports in microfluidic methods for isolation of CTCs and subsequent cellular analysis on them.
Research Area(s)
- Circulating tumor cell, Dielectrophoresis, Immunoaffinity, Immunomagnetic, Microfluidics, Size-based separation
Bibliographic Note
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Citation Format(s)
Microfluidic devices for circulating tumor cells isolation and subsequent analysis. / Khamenehfar, Avid; Li, Paul C.H.
In: Current Pharmaceutical Biotechnology, Vol. 17, No. 9, 01.07.2016, p. 810-821.
In: Current Pharmaceutical Biotechnology, Vol. 17, No. 9, 01.07.2016, p. 810-821.
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
