Abstract
In the study, we report a microfluidic-based dispenser fabricated by standard soft lithography of PDMS (polydimethylsiloxane) for sub-microliter range precise pipetting. The key feature of the microfluidic-based dispenser is the incorporation of a pressure-generating unit providing the driving force for precise and quick aqueous liquid sampling and pipetting. The microfluidic-based dispenser features in the elegant control of the releasing time of the air pressure in the pneumatic chamber of the pressure-generating unit causing the underside membrane to provide suction, thus contributing to precise pipetting of aqueous liquid volumes ranging from 0.05 μ1 to 0.45 μ1 (the minimum unit is 0.05 μ1) achieving the multi-volume dispensing capability. Therefore, the developed microfluidic-based dispenser can dispense multiple sub-microliter aqueous liquid volumes precisely and quickly and is promising for further micro-total-analysis-systems in the field of drug dosing orother biomedical applications. ©2009 IEEE.
| Original language | English |
|---|---|
| Article number | 4805432 |
| Pages (from-to) | 515-518 |
| Journal | Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) |
| DOIs | |
| Publication status | Published - 2009 |
| Externally published | Yes |
| Event | 22nd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2009 - Sorrento, Italy Duration: 25 Jan 2009 → 29 Jan 2009 https://www.memsconferences.org/mems2009/ |
Bibliographical note
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