Microbiota of pregnancy, placenta and newborns in the third trimester : A randomized controlled study

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

4 Scopus Citations
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Author(s)

  • Zhe Li
  • Yiwen Zhang
  • Li Wang
  • Tye Kian Deng
  • Wei-Hsiu Chiu
  • Chengfang Xu
  • Xiaomin Xiao

Detail(s)

Original languageEnglish
Article numbere24698
Journal / PublicationHeliyon
Volume10
Issue number3
Online published19 Jan 2024
Publication statusPublished - 15 Feb 2024

Link(s)

Abstract

Microbiota in pregnant time is vital to healthy of pregnant women and their offspring. However, few study evaluate the composition of the microbiota of health pregnancy, placenta and their newborns at different stages and the origin of the placental microbiota. Samples were obtained from a total of 31 pregnant individuals and their offspring, analyzing by 16S rRNA amplicon sequencing of the V4 region to evaluate the composition and variation of them. We found that the microbiota of pregnant individuals changes in the third trimester. The placental microbiota has its own specific dominant microbiota. The placental microbiota is correlated with the pregnancy microbiota in the gut and vagina at 32–34 weeks but not at full term. The gut microbiota in newborns changes over the first 14 days. © 2024 The Author(s)

Research Area(s)

  • Fetus, Gestational, Gut microbiota, Placenta, Vaginal microbiota

Citation Format(s)

Microbiota of pregnancy, placenta and newborns in the third trimester: A randomized controlled study. / Li, Zhe; Zhang, Yiwen; Wang, Li et al.
In: Heliyon, Vol. 10, No. 3, e24698, 15.02.2024.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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