Mice learn from the predator-attack experience to accelerate flight behavior via optimizing the strategy of environment exploration

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

View graph of relations

Author(s)

  • Jinling Zhong
  • Qingqing Liu
  • Xing Yang
  • Junying Su
  • Xiaofen Li
  • Liping Wang

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)26-34
Journal / PublicationBiochemical and Biophysical Research Communications
Volume665
Online published25 Apr 2023
Publication statusPublished - 12 Jul 2023

Link(s)

Abstract

Efficiently avoiding predators is critical for animal survival. However, little is known about how the experience of predator attack affects behaviors in predator defense. Here, we caught mice by tail to simulate a predator attack. We found that the experienced mice accelerated the flight in response to the visual threaten cue. Single predator attack didn't induce anxiety but increased the activity of innate fear or learning related nucleus. The predator attack induced acceleration of flight was partly rescued when we used drug to block protein synthesis which is critical in the learning process. The experienced mice significantly reduced the focused exploration on the floor during the environment exploration, which might facilitate the discovery of predator. These results suggest that mice could learn from the experience of predator attack to optimize their behavioral pattern to detect the predator cue immediately and response intensely, and therefore increase the probability of survival. © 2023 The Authors.

Research Area(s)

  • Environment exploration, Experience, Innate fear, Learning, Predator attack

Citation Format(s)

Mice learn from the predator-attack experience to accelerate flight behavior via optimizing the strategy of environment exploration. / Zhong, Jinling; Liu, Qingqing; Yang, Xing et al.
In: Biochemical and Biophysical Research Communications, Vol. 665, 12.07.2023, p. 26-34.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

Download Statistics

No data available