Metalated Chromene and Chromone Complexes : pH Switchable Metal–Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
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Detail(s)
Original language | English |
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Pages (from-to) | 1779-1783 |
Journal / Publication | Chemistry - A European Journal |
Volume | 24 |
Issue number | 8 |
Online published | 7 Dec 2017 |
Publication status | Published - 6 Feb 2018 |
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Abstract
The two families of RuII-chromene and -chromone complexes isolated in this work represent the first examples of metalated chromene and chromone complexes synthesized through transition-metal-mediated cyclization of phenol-tethered ynone. These unprecedented metalated heterocyclic compounds exhibit remarkable features, such as pH-switchable metal–carbon bonding interactions, photo-triggerable release of organic chromone upon visible-light irradiation, and superior antioxidative property to their organic analogue (1,4-benzopyrone). These findings not only offer mechanistic insights into metal-induced activation of functionalized alkynes, but also add a new dimension to rational design of antioxidants and photo-responsive drug delivery systems.
Research Area(s)
- alkynes, antioxidants, chromones, photochemistry, ruthenium
Citation Format(s)
Metalated Chromene and Chromone Complexes : pH Switchable Metal–Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity. / Ng, Sze-Wing; Chung, Lai-Hon; Yeung, Chi-Fung; Lo, Hoi-Shing; Shek, Hau-Lam; Kang, Tian-Shu; Leung, Chung-Hang; Ma, Dik-Lung; Wong, Chun-Yuen.
In: Chemistry - A European Journal, Vol. 24, No. 8, 06.02.2018, p. 1779-1783.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review