@inbook{a32c67d83123416ba5d3032d3b21f283,
title = "Meroterpenoids",
abstract = "The fungal meroterpenoids comprise structurally diverse compounds with a wide range of biological activities, and the elucidation of their biosynthetic pathways is important for future drug discovery. Recent advances in genome sequencing have revealed many biosynthetic gene clusters for fungal meroterpenoids, thus providing clearer insights into the enzymes that construct these structurally complex molecules and the genetic bases for the production of these diversified compounds in nature. The roles of these biosynthetic genes have been studied by several approaches, including gene disruption and heterologous expression experiments. Here we present recent examples of the discoveries of the biosynthetic clusters for several meroterpenoids and the functional characterizations of their genes, including the biosynthetic genes for pyripyropene A, meroterpenoids derived from 3,5-dimethylorsellinic acid, and indole-diterpenes.",
keywords = "Biosynthetic Pathway, Biosynthetic Gene, Biosynthetic Gene Cluster , Flavin Adenine Dinucleotide , Geranylgeranyl Pyrophosphate ",
author = "Yudai Matsuda and Ikuro Abe",
year = "2014",
doi = "10.1007/978-1-4939-1191-2\_13",
language = "English",
isbn = "978-1-4939-1190-5",
series = "Fungal Biology ",
publisher = "Springer New York",
pages = "289--301",
editor = "Mart{\'i}n, \{Juan-Francisco \} and Garc{\'i}a-Estrada, \{Carlos \} and Zeilinger, \{Susanne \}",
booktitle = "Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites",
address = "United States",
}