Manipulating exciton dynamics of thermally activated delayed fluorescence materials for tuning two-photon nanotheranostics

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Jia-Xiong Chen
  • Shengliang Li
  • Wen-Wen Tao
  • Kai Wang
  • Xaio-Hong Zhang

Detail(s)

Original languageEnglish
Pages (from-to)888–895
Journal / PublicationChemical Science
Volume11
Issue number3
Online published11 Dec 2019
Publication statusPublished - 21 Jan 2020

Abstract

Rational manipulation of energy utilization from excited-state radiation of theranostic agents with a donor– acceptor structure is relatively unexplored. Herein, we present an effective strategy to tune the exciton dynamics of radiative excited state decay for augmenting two-photon nanotheranostics. As a proof of concept, two thermally activated delayed fluorescence (TADF) molecules with different electrondonating segments are engineered, which possess donor–acceptor structures and strong emissions in the deep-red region with aggregation-induced emission characteristics. Molecular simulations demonstrate that change of the electron-donating sections could effectively regulate the singlet–triplet energy gap and oscillator strength, which promises efficient energy flow. A two-photon laser with great permeability is used to excite TADF NPs to perform as theranostic agents with singlet oxygen generation and fluorescence imaging. These unique performances enable the proposed TADF emitters to exhibit tailored balances between two-photon singlet oxygen generation and fluorescence emission. This result demonstrates that TADF emitters can be rationally designed as superior candidates for nanotheranostic agents by the custom controlling exciton dynamics.

Citation Format(s)

Manipulating exciton dynamics of thermally activated delayed fluorescence materials for tuning two-photon nanotheranostics. / Xiao, Ya-Fang; Chen, Jia-Xiong; Li, Shengliang; Tao, Wen-Wen; Tian, Shuang; Wang, Kai; Cui, Xiao; Huang, Zhongming; Zhang, Xaio-Hong; Lee, Chun-Sing.

In: Chemical Science, Vol. 11, No. 3, 21.01.2020, p. 888–895.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal