Magnetization transfer contrast (MTC) suppressed relayed nuclear Overhauser enhancement (rNOE) imaging at 3 T

Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Abstractpeer-review

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Author(s)

  • Lin Chen
  • Xiang Xu
  • Peter C. M. van Zijl
  • Jiadi Xu

Related Research Unit(s)

Detail(s)

Original languageEnglish
Publication statusPublished - Aug 2020

Conference

TitleISMRM & SMRT Virtual Conference & Exhibition
Period8 - 14 August 2020

Abstract

Relayed nuclear Overhauser enhancement (rNOE) imaging indirectly detects the aliphatic groups of biomolecules and can be used to diagnose protein or lipid signals and related pathology involving such signals. Current rNOE imaging has been studied mainly on high-field MRI scanners (≥7T). When implementing the technique on low clinical MRI fields (≤3T), rNOE contrast is more obscured by semisolid magnetization transfer contrast (MTC) and water direct saturation (DS). We developed a pulsed-CEST/MT method at 3T MRI that can suppress MTC and DS efficiently, not compromising rNOE contrast.

Citation Format(s)

Magnetization transfer contrast (MTC) suppressed relayed nuclear Overhauser enhancement (rNOE) imaging at 3 T. / Huang, Jianpan; Han, Xiongqi; Chen, Lin; Xu, Xiang; van Zijl, Peter C. M.; Xu, Jiadi; Chan, Kannie W. Y.

2020. Abstract from ISMRM & SMRT Virtual Conference & Exhibition, .

Research output: Conference Papers (RGC: 31A, 31B, 32, 33)Abstractpeer-review