Magnetic Nanoparticles for Bioseparation, Biosensing, and Regenerative Medicine

Yiyuan Han; Min Wang; Chenjie Xu

doi:10.1002/9783527803255.ch11

Magnetic Nanoparticles for Bioseparation, Biosensing, and Regenerative Medicine

Yiyuan Han
, Min Wang
, Chenjie Xu

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 12 - Chapter in an edited book (Author) › peer-review

3 Citations (Scopus)

Abstract

This chapter introduces the roles of the rationally designed magnetic nanoparticles (MNPs) for bioseparation, biosensing and tissue engineering/regenerative medicine. It examines the synthesis and modification of MNPs, followed by their applications in bioseparation, biosensing, and regenerative medicine. MNPs were initially synthesized through coprecipitation of ferrous and ferric ions in the basic solution while taking dextran or its derivatives as the coating. Most of the clinically used MNPs such as CosmoFerINFeD Ferrisat (Pharmacosmos) and Feridex I.V. (AMAG) Endorem are prepared with this protocol. Bioseparation is a key step in most biotechnology and bioprocess. It purifies or removes biologics from their respective starting material, for example, cell culture media. Biosensing is another area where MNPs have received great attention. The major advantage of MNPs comes from the lack of magnetic background from biological samples, which allows the sensitive measurements. © 2017 Wiley-VCH Verlag GmbH & Co.

Original language	English
Title of host publication	Magnetic Nanomaterials: Fundamentals, Synthesis and Applications
Publisher	Wiley
Pages	345-364
ISBN (Print)	9783527803255, 9783527341344
DOIs	https://doi.org/10.1002/9783527803255.ch11
Publication status	Published - 1 Jan 2017
Externally published	Yes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Funding

This research project was financially supported by the Beijing Nova and Leading Talents Cultivation Program (No. Z1511000003150147) and the National Natural Science Foundation (No. 51571034).

Research Keywords

biosensing
bioseparation
magnetic force-based tissue engineering
magnetic nanoparticles
regenerative medicine

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AU - Wang, Min

AU - Xu, Chenjie

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N2 - This chapter introduces the roles of the rationally designed magnetic nanoparticles (MNPs) for bioseparation, biosensing and tissue engineering/regenerative medicine. It examines the synthesis and modification of MNPs, followed by their applications in bioseparation, biosensing, and regenerative medicine. MNPs were initially synthesized through coprecipitation of ferrous and ferric ions in the basic solution while taking dextran or its derivatives as the coating. Most of the clinically used MNPs such as CosmoFerINFeD Ferrisat (Pharmacosmos) and Feridex I.V. (AMAG) Endorem are prepared with this protocol. Bioseparation is a key step in most biotechnology and bioprocess. It purifies or removes biologics from their respective starting material, for example, cell culture media. Biosensing is another area where MNPs have received great attention. The major advantage of MNPs comes from the lack of magnetic background from biological samples, which allows the sensitive measurements. © 2017 Wiley-VCH Verlag GmbH & Co.

AB - This chapter introduces the roles of the rationally designed magnetic nanoparticles (MNPs) for bioseparation, biosensing and tissue engineering/regenerative medicine. It examines the synthesis and modification of MNPs, followed by their applications in bioseparation, biosensing, and regenerative medicine. MNPs were initially synthesized through coprecipitation of ferrous and ferric ions in the basic solution while taking dextran or its derivatives as the coating. Most of the clinically used MNPs such as CosmoFerINFeD Ferrisat (Pharmacosmos) and Feridex I.V. (AMAG) Endorem are prepared with this protocol. Bioseparation is a key step in most biotechnology and bioprocess. It purifies or removes biologics from their respective starting material, for example, cell culture media. Biosensing is another area where MNPs have received great attention. The major advantage of MNPs comes from the lack of magnetic background from biological samples, which allows the sensitive measurements. © 2017 Wiley-VCH Verlag GmbH & Co.

KW - biosensing

KW - bioseparation

KW - magnetic force-based tissue engineering

KW - magnetic nanoparticles

KW - regenerative medicine

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M3 - RGC 12 - Chapter in an edited book (Author)

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SN - 9783527341344

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BT - Magnetic Nanomaterials: Fundamentals, Synthesis and Applications

PB - Wiley

ER -

Magnetic Nanoparticles for Bioseparation, Biosensing, and Regenerative Medicine

Abstract

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