Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: Cellular characterization and mitochondria-specific localization

Zhengqing Guo; Wah-Leung Tong; Michael C. W. Chan

doi:10.1039/c3cc47150k

Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: Cellular characterization and mitochondria-specific localization

Zhengqing Guo, Wah-Leung Tong, Michael C. W. Chan

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

28 Citations (Scopus)

Abstract

A readily tunable series of non-planar oligo(ethylene glycol)-substituted phosphorescent Pt(ii) complexes has been investigated as live cell imaging agents; suitable structural modifications can give good cellular uptake, traceable mitochondria-specific localization and potent cytotoxic characteristics towards HeLa cells. © 2014 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	1711-1714
Journal	Chemical Communications
Volume	50
Issue number	14
Online published	4 Dec 2013
DOIs	https://doi.org/10.1039/c3cc47150k
Publication status	Published - 18 Feb 2014

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title = "Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: Cellular characterization and mitochondria-specific localization",

abstract = "A readily tunable series of non-planar oligo(ethylene glycol)-substituted phosphorescent Pt(ii) complexes has been investigated as live cell imaging agents; suitable structural modifications can give good cellular uptake, traceable mitochondria-specific localization and potent cytotoxic characteristics towards HeLa cells. {\textcopyright} 2014 The Royal Society of Chemistry.",

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Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: Cellular characterization and mitochondria-specific localization. / Guo, Zhengqing; Tong, Wah-Leung; Chan, Michael C. W.
In: Chemical Communications, Vol. 50, No. 14, 18.02.2014, p. 1711-1714.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes

T2 - Cellular characterization and mitochondria-specific localization

AU - Guo, Zhengqing

AU - Tong, Wah-Leung

AU - Chan, Michael C. W.

PY - 2014/2/18

Y1 - 2014/2/18

N2 - A readily tunable series of non-planar oligo(ethylene glycol)-substituted phosphorescent Pt(ii) complexes has been investigated as live cell imaging agents; suitable structural modifications can give good cellular uptake, traceable mitochondria-specific localization and potent cytotoxic characteristics towards HeLa cells. © 2014 The Royal Society of Chemistry.

AB - A readily tunable series of non-planar oligo(ethylene glycol)-substituted phosphorescent Pt(ii) complexes has been investigated as live cell imaging agents; suitable structural modifications can give good cellular uptake, traceable mitochondria-specific localization and potent cytotoxic characteristics towards HeLa cells. © 2014 The Royal Society of Chemistry.

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DO - 10.1039/c3cc47150k

M3 - RGC 21 - Publication in refereed journal

C2 - 24396855

SN - 0009-241X

VL - 50

SP - 1711

EP - 1714

JO - Chemical Communications

JF - Chemical Communications

IS - 14

ER -

Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: Cellular characterization and mitochondria-specific localization

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