Linear processing of spatial cues in primary auditory cortex

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)200-204
Journal / PublicationNature
Volume414
Issue number6860
StatePublished - 8 Nov 2001
Externally publishedYes

Abstract

To determine the direction of a sound source in space, animals must process a variety of auditory spatial cues, including interaural level and time differences, as well as changes in the sound spectrum caused by the direction-dependent filtering of sound by the outer ear1. Behavioural deficits observed when primary auditory cortex (Al) is damaged have led to the widespread view that A1 may have an essential role in this complex computational task2-5. Here we show, however, that the spatial selectivity exhibited by the large majority of A1 neurons is well predicted by a simple linear model, which assumes that neurons additively integrate sound levels in each frequencyband and ear. The success of this linear model is surprising, given that computing sound source direction is a necessarily nonlinear operation6-9. However, because linear operations preserve information, our results are consistent with the hypothesis that A1 may also form a gateway to higher, more specialized cortical areas10-11.

Citation Format(s)

Linear processing of spatial cues in primary auditory cortex. / Schnupp, J. W H D; Mrsic-Flogel, T.; King, A. J.

In: Nature, Vol. 414, No. 6860, 08.11.2001, p. 200-204.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal