Lift-off cell lithography for cell patterning with clean background

Cong Wu; Xiongfeng Zhu; Tianxing Man; Pei-Shan Chung; Michael A. Teitell; Pei-Yu Chiou

doi:10.1039/c8lc00726h

Lift-off cell lithography for cell patterning with clean background

Cong Wu, Xiongfeng Zhu, Tianxing Man, Pei-Shan Chung, Michael A. Teitell, Pei-Yu Chiou^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

27 Citations (Scopus)

Abstract

We developed a highly efficient method for patterning cells by a novel and simple technique called lift-off cell lithography (LCL). Our approach borrows the key concept of lift-off lithography from microfabrication and utilizes a fully biocompatible process to achieve high-throughput, high-efficiency cell patterning with nearly zero background defects across a large surface area. Using LCL, we reproducibly achieved >70% patterning efficiency for both adherent and non-adherent cells with <1% defects in undesired areas.

Original language	English
Pages (from-to)	3074-3078
Journal	Lab on a Chip
Volume	18
Issue number	20
Online published	31 Aug 2018
DOIs	https://doi.org/10.1039/c8lc00726h
Publication status	Published - 21 Oct 2018

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abstract = "We developed a highly efficient method for patterning cells by a novel and simple technique called lift-off cell lithography (LCL). Our approach borrows the key concept of lift-off lithography from microfabrication and utilizes a fully biocompatible process to achieve high-throughput, high-efficiency cell patterning with nearly zero background defects across a large surface area. Using LCL, we reproducibly achieved >70% patterning efficiency for both adherent and non-adherent cells with <1% defects in undesired areas.",

author = "Cong Wu and Xiongfeng Zhu and Tianxing Man and Pei-Shan Chung and Teitell, {Michael A.} and Pei-Yu Chiou",

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TY - JOUR

T1 - Lift-off cell lithography for cell patterning with clean background

AU - Wu, Cong

AU - Zhu, Xiongfeng

AU - Man, Tianxing

AU - Chung, Pei-Shan

AU - Teitell, Michael A.

AU - Chiou, Pei-Yu

PY - 2018/10/21

Y1 - 2018/10/21

N2 - We developed a highly efficient method for patterning cells by a novel and simple technique called lift-off cell lithography (LCL). Our approach borrows the key concept of lift-off lithography from microfabrication and utilizes a fully biocompatible process to achieve high-throughput, high-efficiency cell patterning with nearly zero background defects across a large surface area. Using LCL, we reproducibly achieved >70% patterning efficiency for both adherent and non-adherent cells with <1% defects in undesired areas.

AB - We developed a highly efficient method for patterning cells by a novel and simple technique called lift-off cell lithography (LCL). Our approach borrows the key concept of lift-off lithography from microfabrication and utilizes a fully biocompatible process to achieve high-throughput, high-efficiency cell patterning with nearly zero background defects across a large surface area. Using LCL, we reproducibly achieved >70% patterning efficiency for both adherent and non-adherent cells with <1% defects in undesired areas.

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85054703042&origin=recordpage

U2 - 10.1039/c8lc00726h

DO - 10.1039/c8lc00726h

M3 - RGC 21 - Publication in refereed journal

C2 - 30183051

SN - 1473-0197

VL - 18

SP - 3074

EP - 3078

JO - Lab on a Chip

JF - Lab on a Chip

IS - 20

ER -

Lift-off cell lithography for cell patterning with clean background

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