Abstract
Objective: To study the main chemical constituents in Buzhongyigi Tang (BYT) and its regulating effect on immune-depressed mice treated by cyclophosphomide (CY). Methods: LC-MS Analysis of BYT, inhibitory effect of T, B lymphocyte cell proliferation and NK cell activity were observed by MTT method. Results: The main chemical constituents of BYT are polysarccharides, flavonoids, and saponins, they significantly improve the T, B lymphocyte cell proliferation and NK activity in immune-depressed mice treated by CY. Conclusion: The LC-MS method could be used in studying on active constituents in Chinese compound formula so as to elucidate their material bases of pharmacology.
| Original language | English |
|---|---|
| Pages (from-to) | 1134-1137 |
| Journal | Chinese Traditional and Herbal Drugs |
| Volume | 37 |
| Issue number | 8 |
| Publication status | Published - Aug 2006 |
Research Keywords
- Buzhongyiqi Tang (BYT)
- Cyclophophomide (CY)
- Immunology
- LC-MS
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