Layered double hydroxide nanostructures and nanocomposites for biomedical applications

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

19 Scopus Citations
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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)5583-5601
Journal / PublicationJournal of Materials Chemistry B
Volume7
Issue number37
Online published29 Aug 2019
Publication statusPublished - 7 Oct 2019

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Abstract

Layered double hydroxide (LDH) nanostructures and related nanocomposites have attracted significant interest in biomedical applications including cancer therapy, bioimaging and antibacterial treatment. These materials hold great advantages including low cost and facile preparation, convenient drug loading, high drug incorporation capacity, good biocompatibility, efficient intracellular uptake and endosome/lysosome escape, and natural biodegradability in an acidic environment. In this review, we summarize the development of three types of LDH nanostructures including pristine LDH, surface modified LDH, and LDH nanocomposites for a range of biomedical applications. The advantages and disadvantages of LDH nanostructures and insights into the future development are also discussed.

Research Area(s)

  • DIAMOND-NANONEEDLE-ARRAY, MESOPOROUS SILICA SHELL, REDUCED GRAPHENE OXIDE, DRUG-DELIVERY, CONTROLLED-RELEASE, GENE-THERAPY, CO-DELIVERY, INTRACELLULAR DELIVERY, COLLOIDAL STABILITY, ESCHERICHIA-COLI

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