Abstract
The paper reviews the state-of-art for micro optical fluidic systems (MOFS), or optofluidics, which employs optics and fluidics in a microsystem environment to perform novel functionalities and in-depth analysis in the biophysical area. Various topics, which include the introduction of MOFS in biomedical engineering, the implementation of near-field optics and also the applications of MOFS to biophysical studies, are discussed. Different optical detection techniques, such as evanescent wave, surface plasmon resonance, surface enhanced Raman scattering, resonators and transistors, have been studied extensively and integrated into MOFS. In addition, MOFS also provides a platform for various studies of cell biophysics, such as cell mass determination and cell Young's modulus measurement. © 2008 Springer-Verlag.
| Original language | English |
|---|---|
| Pages (from-to) | 2443-2452 |
| Journal | Analytical and Bioanalytical Chemistry |
| Volume | 391 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Aug 2008 |
| Externally published | Yes |
Bibliographical note
Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].Research Keywords
- Cell biophysics
- Micro optical fluidic system
- Optofluidics
- Resonator
- Surface enhanced Raman scattering
- Surface plasmon resonance