Isotropic-resolution linear-array-based photoacoustic computed tomography through inverse Radon transform

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

7 Scopus Citations
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Author(s)

Detail(s)

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume9323
ISBN (print)9781628414134
Publication statusPublished - 2015
Externally publishedYes

Publication series

Name
Volume9323
ISSN (Print)1605-7422

Conference

TitlePhotons Plus Ultrasound: Imaging and Sensing 2015
PlaceUnited States
CitySan Francisco
Period8 - 10 February 2015

Abstract

Linear transducer arrays are readily available for ultrasonic detection in photoacoustic computed tomography. They offer low cost, hand-held convenience, and conventional ultrasonic imaging. However, the elevational resolution of linear transducer arrays, which is usually determined by the weak focus of the cylindrical acoustic lens, is about one order of magnitude worse than the in-plane axial and lateral spatial resolutions. Therefore, conventional linear scanning along the elevational direction cannot provide high-quality three-dimensional photoacoustic images due to the anisotropic spatial resolutions. Here we propose an innovative method to achieve isotropic resolutions for three-dimensional photoacoustic images through combined linear and rotational scanning. In each scan step, we first elevationally scan the linear transducer array, and then rotate the linear transducer array along its center in small steps, and scan again until 180 degrees have been covered. To reconstruct isotropic three-dimensional images from the multiple-directional scanning dataset, we use the standard inverse Radon transform originating from X-ray CT. We acquired a three-dimensional microsphere phantom image through the inverse Radon transform method and compared it with a single-elevational-scan three-dimensional image. The comparison shows that our method improves the elevational resolution by up to one order of magnitude, approaching the in-plane lateral-direction resolution. In vivo rat images were also acquired.

Research Area(s)

  • Inverse Radon transform, Isotropic resolution, Linear transducer array, Photoacoustic computed tomography

Citation Format(s)

Isotropic-resolution linear-array-based photoacoustic computed tomography through inverse Radon transform. / Li, Guo; Xia, Jun; Li, Lei et al.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 9323 SPIE, 2015. 93230I.

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review