Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

1 Scopus Citations
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Author(s)

  • Xing-Ren Li
  • Qiang Fu
  • Min Zhou
  • Kun Hu
  • Xue Du
  • Xiao-Nian Li
  • Han-Dong Sun
  • Hong-Bin Zhang
  • Pema-Tenzin Puno

Detail(s)

Original languageEnglish
Pages (from-to)977-984
Journal / PublicationJournal of Asian Natural Products Research
Volume21
Issue number10
Online published6 Jun 2018
Publication statusPublished - 2019

Abstract

Two new ent-clerodane diterpenoids, named isoscoparins R and S (1 and 2), were isolated from the aerial parts of Isodon scoparius. Their structures were characterized mainly by analyzing the NMR and HRESIMS data, and the relative configuration of compound 1 was determined by single-crystal X-ray diffraction. Compound 2 showed weak activity as an autophagic inhibitor.

Research Area(s)

  • autophagic activity, ent-clerodane diterpenoids, Isodon scoparius, Lamiaceae, X-ray diffraction

Citation Format(s)

Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius. / Li, Xing-Ren; Fu, Qiang; Zhou, Min; Hu, Kun; Du, Xue; Li, Xiao-Nian; Sun, Han-Dong; Yue, Jian-Bo; Zhang, Hong-Bin; Puno, Pema-Tenzin.

In: Journal of Asian Natural Products Research, Vol. 21, No. 10, 2019, p. 977-984.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal