TY - JOUR
T1 - Interstitial fluid-based wearable biosensors for minimally invasive healthcare and biomedical applications
AU - Wu, Zixiong
AU - Qiao, Zheng
AU - Chen, Shuwen
AU - Fan, Shicheng
AU - Liu, Yuanchao
AU - Qi, Jiaming
AU - Lim, Chwee Teck
PY - 2024
Y1 - 2024
N2 - Interstitial fluid (ISF), a biological fluid rich in diverse biomarkers and analytes and similar to blood composition, has garnered significant attention as a valuable source of clinically relevant information. Consequently, ISF-based wearable biosensors are emerging as powerful tools for non-invasive and minimally invasive disease diagnosis, personalized medicine, and other healthcare and biomedical applications. This review provides a comprehensive overview of recent advancements in ISF-based biosensors, with a particular focus on wearable ISF sensors. We first offer insights into ISF biomarkers and sampling techniques and discuss recent ISF sensing strategies that encompass materials, fabrication methods, and sensing mechanisms. Then, we present a comprehensive overview of their applications. Finally, we address the challenges faced in this field and offer a forward-looking perspective on promising future directions. © The Author(s) 2024.
AB - Interstitial fluid (ISF), a biological fluid rich in diverse biomarkers and analytes and similar to blood composition, has garnered significant attention as a valuable source of clinically relevant information. Consequently, ISF-based wearable biosensors are emerging as powerful tools for non-invasive and minimally invasive disease diagnosis, personalized medicine, and other healthcare and biomedical applications. This review provides a comprehensive overview of recent advancements in ISF-based biosensors, with a particular focus on wearable ISF sensors. We first offer insights into ISF biomarkers and sampling techniques and discuss recent ISF sensing strategies that encompass materials, fabrication methods, and sensing mechanisms. Then, we present a comprehensive overview of their applications. Finally, we address the challenges faced in this field and offer a forward-looking perspective on promising future directions. © The Author(s) 2024.
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U2 - 10.1038/s43246-024-00468-6
DO - 10.1038/s43246-024-00468-6
M3 - RGC 21 - Publication in refereed journal
SN - 2662-4443
VL - 5
JO - Communications Materials
JF - Communications Materials
M1 - 33
ER -