Intérêt du test AlaSTAT pour la mise en évidence d'IgE spécifiques aux allergènes alimentaires: Étude comparative avec le RAST Phadebas Cap System

D.A Moneret-Vautrin; G. Halpern; G. Kanny; J. Brignon; J.P. Nicolas

doi:10.1016/S0335-7457(05)80357-0

Intérêt du test AlaSTAT pour la mise en évidence d'IgE spécifiques aux allergènes alimentaires: Étude comparative avec le RAST Phadebas Cap System

Translated title of the contribution: Value of the AlaSTAT test in demonstrating specific IgE in food allergies: Comparative study with the RAST Phadebas Cap System

D.A Moneret-Vautrin^*, G. Halpern, G. Kanny, J. Brignon, J.P. Nicolas

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

3 Citations (Scopus)

Abstract

49 sera from patients with food allergies confirmed by challenge, and 26 with suspected ones were assayed with the DPC AlaSTAT liquid phase EIA, and the Phadebas RAST CAP RIA. 22 foods were tested (4 animals, 18 vegetables). Controls were performed on non-atopics (N = 8) and atopics (N = 8). Specificity was 100 %. Sensitivity was 76 % (animals) and 73 % (vegetables) (87 % for prick-tests, 76 % for RAST). Concordance RAST CAP/AlaSTAT was 79.6 % ; prick-tests/AlaSTAT : 76 % ; prick-tests/RAST CAP : 73.9 %. AlaSTAT detected specific IgE even in sera with low total IgE (<60 KU/l), while RAST CAP was inconclusive. Dilution studies and reproductibility were excellent. AlaSTAT EIA compares favorably with the Phadebas RAST CAP RIA for measurement of food specific IgE antibodies. © 1992 Published by Elsevier Masson SAS.

Translated title of the contribution	Value of the AlaSTAT test in demonstrating specific IgE in food allergies: Comparative study with the RAST Phadebas Cap System
Original language	French
Pages (from-to)	188-195
Journal	Revue Francaise d'Allergologie et d'Immunologie Clinique
Volume	32
Issue number	4
DOIs	https://doi.org/10.1016/S0335-7457(05)80357-0
Publication status	Published - Oct 1992
Externally published	Yes

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@article{6075d493495c4078898b61ed0ca38a88,

title = "Int{\'e}r{\^e}t du test AlaSTAT pour la mise en {\'e}vidence d'IgE sp{\'e}cifiques aux allerg{\`e}nes alimentaires: {\'E}tude comparative avec le RAST Phadebas Cap System",

abstract = "49 sera from patients with food allergies confirmed by challenge, and 26 with suspected ones were assayed with the DPC AlaSTAT liquid phase EIA, and the Phadebas RAST CAP RIA. 22 foods were tested (4 animals, 18 vegetables). Controls were performed on non-atopics (N = 8) and atopics (N = 8). Specificity was 100 %. Sensitivity was 76 % (animals) and 73 % (vegetables) (87 % for prick-tests, 76 % for RAST). Concordance RAST CAP/AlaSTAT was 79.6 % ; prick-tests/AlaSTAT : 76 % ; prick-tests/RAST CAP : 73.9 %. AlaSTAT detected specific IgE even in sera with low total IgE (<60 KU/l), while RAST CAP was inconclusive. Dilution studies and reproductibility were excellent. AlaSTAT EIA compares favorably with the Phadebas RAST CAP RIA for measurement of food specific IgE antibodies. {\textcopyright} 1992 Published by Elsevier Masson SAS.",

author = "D.A Moneret-Vautrin and G. Halpern and G. Kanny and J. Brignon and J.P. Nicolas",

year = "1992",

month = oct,

doi = "10.1016/S0335-7457(05)80357-0",

language = "French",

volume = "32",

pages = "188--195",

journal = "Revue Francaise d'Allergologie et d'Immunologie Clinique",

issn = "0335-7457",

publisher = "Elsevier Masson SAS",

number = "4",

}

Intérêt du test AlaSTAT pour la mise en évidence d'IgE spécifiques aux allergènes alimentaires: Étude comparative avec le RAST Phadebas Cap System. / Moneret-Vautrin, D.A; Halpern, G.; Kanny, G. et al.
In: Revue Francaise d'Allergologie et d'Immunologie Clinique, Vol. 32, No. 4, 10.1992, p. 188-195.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Intérêt du test AlaSTAT pour la mise en évidence d'IgE spécifiques aux allergènes alimentaires

T2 - Étude comparative avec le RAST Phadebas Cap System

AU - Moneret-Vautrin, D.A

AU - Halpern, G.

AU - Kanny, G.

AU - Brignon, J.

AU - Nicolas, J.P.

PY - 1992/10

Y1 - 1992/10

N2 - 49 sera from patients with food allergies confirmed by challenge, and 26 with suspected ones were assayed with the DPC AlaSTAT liquid phase EIA, and the Phadebas RAST CAP RIA. 22 foods were tested (4 animals, 18 vegetables). Controls were performed on non-atopics (N = 8) and atopics (N = 8). Specificity was 100 %. Sensitivity was 76 % (animals) and 73 % (vegetables) (87 % for prick-tests, 76 % for RAST). Concordance RAST CAP/AlaSTAT was 79.6 % ; prick-tests/AlaSTAT : 76 % ; prick-tests/RAST CAP : 73.9 %. AlaSTAT detected specific IgE even in sera with low total IgE (<60 KU/l), while RAST CAP was inconclusive. Dilution studies and reproductibility were excellent. AlaSTAT EIA compares favorably with the Phadebas RAST CAP RIA for measurement of food specific IgE antibodies. © 1992 Published by Elsevier Masson SAS.

AB - 49 sera from patients with food allergies confirmed by challenge, and 26 with suspected ones were assayed with the DPC AlaSTAT liquid phase EIA, and the Phadebas RAST CAP RIA. 22 foods were tested (4 animals, 18 vegetables). Controls were performed on non-atopics (N = 8) and atopics (N = 8). Specificity was 100 %. Sensitivity was 76 % (animals) and 73 % (vegetables) (87 % for prick-tests, 76 % for RAST). Concordance RAST CAP/AlaSTAT was 79.6 % ; prick-tests/AlaSTAT : 76 % ; prick-tests/RAST CAP : 73.9 %. AlaSTAT detected specific IgE even in sera with low total IgE (<60 KU/l), while RAST CAP was inconclusive. Dilution studies and reproductibility were excellent. AlaSTAT EIA compares favorably with the Phadebas RAST CAP RIA for measurement of food specific IgE antibodies. © 1992 Published by Elsevier Masson SAS.

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U2 - 10.1016/S0335-7457(05)80357-0

DO - 10.1016/S0335-7457(05)80357-0

M3 - RGC 21 - Publication in refereed journal

SN - 0335-7457

VL - 32

SP - 188

EP - 195

JO - Revue Francaise d'Allergologie et d'Immunologie Clinique

JF - Revue Francaise d'Allergologie et d'Immunologie Clinique

IS - 4

ER -

Intérêt du test AlaSTAT pour la mise en évidence d'IgE spécifiques aux allergènes alimentaires: Étude comparative avec le RAST Phadebas Cap System

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