INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS

Sophie Lian; Yi Liu; Rongzhou Lin; John S. Ho; Chia-Hung Chen

INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS

Sophie Lian
, Yi Liu
, Rongzhou Lin
, John S. Ho
, Chia-Hung Chen^*

^*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

A drug delivery system that allows a spatial, flexible and precise control of drug delivery, whilst being minimally invasive has been widely researched, with light stimulated smart hydrogels appearing as an attractive platform. However, as light has limited penetration through biological tissues, we have developed an integrated micro-device comprising of a wireless powered light source, and a photodegradable hydrogel to enable for deep-tissue therapeutics. Midfield wireless power transfer is permitted by the micro-device's miniaturized size, allowing for a penetration depth of several centimetres. Release studies have also shown a sustainable, targeted and controllable cargo release.

Original language	English
Title of host publication	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)
Publisher	Chemical and Biological Microsystems Society
Pages	752-753
ISBN (Print)	9781733419000, 9781713818526
Publication status	Published - Oct 2019
Externally published	Yes
Event	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019) - Congress Center Basel, Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019 https://cbmsociety.org/microtas/microtas2019/

Publication series

Name	International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS

Conference

Conference	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)
Abbreviated title	MicroTAS 2019
Place	Switzerland
City	Basel
Period	27/10/19 → 31/10/19
Internet address	https://cbmsociety.org/microtas/microtas2019/

Research Keywords

Drug delivery
Photodegradable hydrogel
Wireless powering

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Lian, S., Liu, Y., Lin, R., Ho, J. S., & Chen, C.-H. (2019). INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019) (pp. 752-753). (International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS). Chemical and Biological Microsystems Society.

Lian, Sophie ; Liu, Yi ; Lin, Rongzhou et al. / INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS. 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019). Chemical and Biological Microsystems Society, 2019. pp. 752-753 (International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS).

@inproceedings{0804bc482fcc43c8bd6e903887570a41,

title = "INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS",

abstract = "A drug delivery system that allows a spatial, flexible and precise control of drug delivery, whilst being minimally invasive has been widely researched, with light stimulated smart hydrogels appearing as an attractive platform. However, as light has limited penetration through biological tissues, we have developed an integrated micro-device comprising of a wireless powered light source, and a photodegradable hydrogel to enable for deep-tissue therapeutics. Midfield wireless power transfer is permitted by the micro-device's miniaturized size, allowing for a penetration depth of several centimetres. Release studies have also shown a sustainable, targeted and controllable cargo release.",

keywords = "Drug delivery, Photodegradable hydrogel, Wireless powering",

author = "Sophie Lian and Yi Liu and Rongzhou Lin and Ho, \{John S.\} and Chia-Hung Chen",

year = "2019",

month = oct,

language = "English",

isbn = "9781733419000",

series = "International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS",

publisher = "Chemical and Biological Microsystems Society",

pages = "752--753",

booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)",

note = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019), MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",

url = "https://cbmsociety.org/microtas/microtas2019/",

}

Lian, S, Liu, Y, Lin, R, Ho, JS & Chen, C-H 2019, INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS. in 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019). International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS, Chemical and Biological Microsystems Society, pp. 752-753, 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019), Basel, Switzerland, 27/10/19.

INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS. / Lian, Sophie; Liu, Yi; Lin, Rongzhou et al.
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019). Chemical and Biological Microsystems Society, 2019. p. 752-753 (International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS

AU - Lian, Sophie

AU - Liu, Yi

AU - Lin, Rongzhou

AU - Ho, John S.

AU - Chen, Chia-Hung

PY - 2019/10

Y1 - 2019/10

N2 - A drug delivery system that allows a spatial, flexible and precise control of drug delivery, whilst being minimally invasive has been widely researched, with light stimulated smart hydrogels appearing as an attractive platform. However, as light has limited penetration through biological tissues, we have developed an integrated micro-device comprising of a wireless powered light source, and a photodegradable hydrogel to enable for deep-tissue therapeutics. Midfield wireless power transfer is permitted by the micro-device's miniaturized size, allowing for a penetration depth of several centimetres. Release studies have also shown a sustainable, targeted and controllable cargo release.

AB - A drug delivery system that allows a spatial, flexible and precise control of drug delivery, whilst being minimally invasive has been widely researched, with light stimulated smart hydrogels appearing as an attractive platform. However, as light has limited penetration through biological tissues, we have developed an integrated micro-device comprising of a wireless powered light source, and a photodegradable hydrogel to enable for deep-tissue therapeutics. Midfield wireless power transfer is permitted by the micro-device's miniaturized size, allowing for a penetration depth of several centimetres. Release studies have also shown a sustainable, targeted and controllable cargo release.

KW - Drug delivery

KW - Photodegradable hydrogel

KW - Wireless powering

UR - https://www.scopus.com/pages/publications/85094981244

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85094981244&origin=recordpage

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 9781733419000

SN - 9781713818526

T3 - International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS

SP - 752

EP - 753

BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)

PB - Chemical and Biological Microsystems Society

T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)

Y2 - 27 October 2019 through 31 October 2019

ER -

Lian S, Liu Y, Lin R, Ho JS, Chen CH. INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019). Chemical and Biological Microsystems Society. 2019. p. 752-753. (International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS).

INJECTABLE WIRELESS MICRO-DEVICE INTEGRATED WITH PHOTODEGRADABLE HYDROGEL FOR DEEP TISSUE THERAPEUTICS

Abstract

Publication series

Conference

Research Keywords

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