Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
Original language | English |
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Pages (from-to) | 1225-1229 |
Journal / Publication | ChemBioChem |
Volume | 8 |
Issue number | 11 |
Publication status | Published - 23 Jul 2007 |
Link(s)
Abstract
(Figure Presented) Through the wire. We have investigated the potential effects of silicon nanowires (SiNW-SiO2) and SiNWs functionalized with carboxylic groups (SiNW-COOH) on restriction endonucleases and Taq DNA polymerase. The results show that these SiNWs can inhibit enzyme activity (lower band in gel). Our findings suggest that this could be due to chemical interactions between the functional groups on SiNWs and the enzymes. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
Research Area(s)
- DNA, Enzymes, Nanostructures, Polymerase chain reaction
Citation Format(s)
Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities. / Yi, Changqing; Fong, Chi-Chun; Chen, Weiwei et al.
In: ChemBioChem, Vol. 8, No. 11, 23.07.2007, p. 1225-1229.
In: ChemBioChem, Vol. 8, No. 11, 23.07.2007, p. 1225-1229.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review