Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Changqing Yi
  • Chi-Chun Fong
  • Weiwei Chen
  • Suijian Qi
  • Shuit-Tong Lee

Detail(s)

Original languageEnglish
Pages (from-to)1225-1229
Journal / PublicationChemBioChem
Volume8
Issue number11
Publication statusPublished - 23 Jul 2007

Abstract

(Figure Presented) Through the wire. We have investigated the potential effects of silicon nanowires (SiNW-SiO2) and SiNWs functionalized with carboxylic groups (SiNW-COOH) on restriction endonucleases and Taq DNA polymerase. The results show that these SiNWs can inhibit enzyme activity (lower band in gel). Our findings suggest that this could be due to chemical interactions between the functional groups on SiNWs and the enzymes. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

Research Area(s)

  • DNA, Enzymes, Nanostructures, Polymerase chain reaction

Citation Format(s)

Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities. / Yi, Changqing; Fong, Chi-Chun; Chen, Weiwei et al.
In: ChemBioChem, Vol. 8, No. 11, 23.07.2007, p. 1225-1229.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review