Abstract
In this work, we studied alpha-particle induced and medium-mediated bystander effects in Chinese hamster ovary (CHO) cells through micronucleus (MN) assay. We showed that signal transduction from irradiated cells to bystander cells occur within a short time after irradiation. We then studied the effects of ROS (reactive oxygen species)-scavenging catechins in the medium before irradiation. We observed decreases in the percentage of bystander cells with MN formation and thus proved the protection effect of catechins on bystander cells from radiation. © 2009 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 726-729 |
| Journal | Applied Radiation and Isotopes |
| Volume | 68 |
| Issue number | 4-5 |
| DOIs | |
| Publication status | Published - Apr 2010 |
Research Keywords
- Alpha-particle
- Bystander effect
- Catechins
- CHO cells
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