Inactivation effects of non-thermal atmospheric-pressure helium plasma jet on staphylococcus aureus biofilms

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Zimu Xu
  • Jie Shen
  • Zelong Zhang
  • Jie Ma
  • Ronghua Ma
  • Ying Zhao
  • Qiang Sun
  • Shulou Qian
  • Lili Ding
  • Cheng Cheng
  • Weidong Xia

Detail(s)

Original languageEnglish
Pages (from-to)827-835
Journal / PublicationPlasma Processes and Polymers
Volume12
Issue number8
Online published30 Apr 2015
Publication statusPublished - Aug 2015

Abstract

The antimicrobial effects and mechanism of helium atmospheric-pressure plasma jet (APPJ) treatment on Staphylococcus aureus biofilms are evaluated in vitro. The S. aureus biofilms are more resistant to the plasma treatment than adherent bacteria. The APPJ-treated S. aureus biofilms disclose a depth/layer-related intra-bacterial ROS accumulation effect. Plasma exposure may induce bacterial oxidative stress and trigger the production of intracellular reactive oxygen species (ROS) in the biofilms, which possibly contributes to bacteria death in addition to direct etching from the exterior of bacteria. The findings provide insights into the mechanism of biofilm inactivation by plasma reactive species and plasma-induced intracellular ROS.

Research Area(s)

  • microbial biofilm, non-thermal plasma, plasma jet, reactive oxygen species, sterilization/decontamination

Citation Format(s)

Inactivation effects of non-thermal atmospheric-pressure helium plasma jet on staphylococcus aureus biofilms. / Xu, Zimu; Shen, Jie; Zhang, Zelong; Ma, Jie; Ma, Ronghua; Zhao, Ying; Sun, Qiang; Qian, Shulou; Zhang, Hao; Ding, Lili; Cheng, Cheng; Chu, Paul K.; Xia, Weidong.

In: Plasma Processes and Polymers, Vol. 12, No. 8, 08.2015, p. 827-835.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review