Immunological Detection Methods for Biomarkers

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 12 - Chapter in an edited book (Author)peer-review

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Detail(s)

Original languageEnglish
Title of host publicationDetection Methods in Precision Medicine
EditorsMengsu Yang, Michael Thompson
PublisherRoyal Society of Chemistry
Chapter11
Pages223-252
ISBN (electronic)978-1-78801-996-5
ISBN (print)978-1-78801-761-9
Publication statusPublished - 2021

Publication series

NameDetection Science Series
Number18
ISSN (Print)2052-3068
ISSN (electronic)2052-3076

Abstract

Immunological detection methods play an important role in identifying specific biomarkers for disease diagnosis, prognosis, and treatment in precision medicine. With the recent attention shifted towards personalized treatments, immunological detection methods provide a platform for acquiring precise and accurate information using immunoassays. These assays operate on the principle of antigen-antibody interaction to identify disease-specific biomarkers in clinical application. In immunoassays, the antibody-antigen complex is detected through end-reaction outputs that can be analyzed both qualitatively and quantitatively. This book chapter discusses common immunoassays employed in clinical and research settings, emphasizing specificity and accuracy of each method. The chapter will also highlight some recent advancements in immunoassay technology.

Citation Format(s)

Immunological Detection Methods for Biomarkers. / LIM, King Hoo; DOTSE, Eunice; CHOW, Kwan T.
Detection Methods in Precision Medicine. ed. / Mengsu Yang; Michael Thompson. Royal Society of Chemistry, 2021. p. 223-252 (Detection Science Series; No. 18).

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 12 - Chapter in an edited book (Author)peer-review