TY - GEN
T1 - Immobilized liquid coatings for implantable neural electronics
AU - Rutz, Alexandra L.
AU - Carnicer-Lombarte, Alejandro
AU - Barone, Damiano G.
AU - Malliaras, George G.
N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].
PY - 2019/4
Y1 - 2019/4
N2 - Statement of Purpose: Implantable neural electronics are clinically important in many treatments such as deep brain stimulation for Parkinson’s disease, mapping of epileptic foci for surgical resection of the zone as well as in the development of brain-machine interfaces (BMI) for paralyzed individuals. Traditionally, implantable electronics much more resemble the electronics that are used in our everyday technology (computers, phones) than the tissue that surrounds such devices. For this reason, implantable electronics suffer from many limitations that prevent them from realizing full clinical impact. Such limitations include chronic biocompatibility, chronic electronic performance (e.g. biofouling, dielectric degradation) and significant surgical trauma from their implantation. Here, we have investigated immobilized liquid coatings on implantable electronics. Such coatings consist of a water-immiscible liquids (oil) that are anchored to the implant surface by being infused within an elastomer network to shield neural probes from surrounding tissue. Immobilized liquid coatings are slippery (ultralow sliding angles); others have been shown these coatings resist blood cell adhesion and bacterial biofouling. We investigate how such liquid coatings can benefit neural probe applications. © 2019 Omnipress - All rights reserved.
AB - Statement of Purpose: Implantable neural electronics are clinically important in many treatments such as deep brain stimulation for Parkinson’s disease, mapping of epileptic foci for surgical resection of the zone as well as in the development of brain-machine interfaces (BMI) for paralyzed individuals. Traditionally, implantable electronics much more resemble the electronics that are used in our everyday technology (computers, phones) than the tissue that surrounds such devices. For this reason, implantable electronics suffer from many limitations that prevent them from realizing full clinical impact. Such limitations include chronic biocompatibility, chronic electronic performance (e.g. biofouling, dielectric degradation) and significant surgical trauma from their implantation. Here, we have investigated immobilized liquid coatings on implantable electronics. Such coatings consist of a water-immiscible liquids (oil) that are anchored to the implant surface by being infused within an elastomer network to shield neural probes from surrounding tissue. Immobilized liquid coatings are slippery (ultralow sliding angles); others have been shown these coatings resist blood cell adhesion and bacterial biofouling. We investigate how such liquid coatings can benefit neural probe applications. © 2019 Omnipress - All rights reserved.
UR - https://www.scopus.com/pages/publications/85065415197
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85065415197&origin=recordpage
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 9781510883901
VL - 40
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
BT - Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting Part 1
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -