Identifying duplications and lateral gene transfers simultaneously and rapidly

Zhi-Zhong Chen, Fei Deng, Lusheng Wang

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

Abstract

This paper deals with the problem of enumerating all minimum-cost LCA-reconciliations involving gene duplications and lateral gene transfers (LGTs) for a given species tree S and a given gene tree G. Previously, Tofigh et al. [20] gave a fixed-parameter algorithm for this problem that runs in O(m + 3k n) time, where m is the number of vertices in S, n is the number of vertices in G, and k is the minimum cost of an LCA-reconciliation between Sand G. In this paper, by refining their algorithm, we obtain a new one for the same problem that finds and outputs the solutions in a compact form within O(mn2 + 3k) time. © 2013 IEEE.
Original languageEnglish
Title of host publicationProceedings of the IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2013 - 2013 IEEE Symposium Series on Computational Intelligence, SSCI 2013
Pages128-135
DOIs
Publication statusPublished - 2013
Event10th Annual IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2013 - 2013 IEEE Symposium Series on Computational Intelligence, SSCI 2013 - Singapore, Singapore
Duration: 16 Apr 201319 Apr 2013

Conference

Conference10th Annual IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2013 - 2013 IEEE Symposium Series on Computational Intelligence, SSCI 2013
Country/TerritorySingapore
CitySingapore
Period16/04/1319/04/13

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