Hydrothermal synthesis and biocompatibility of hydroxyapatite nanorods

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Original languageEnglish
Pages (from-to)10444-10448
Journal / PublicationJournal of Nanoscience and Nanotechnology
Issue number12
Publication statusPublished - 2011


A facile micelle precursor having cyclohexane/ethanol/cetyl trimethyl ammonium bromide/aqueous phase was treated hydrothermally to form nanohydroxyapatite. The synthesized products were characterized by means of X-ray diffraction, thermogravimetric analysis, transmission electron microscopy and energy-dispersive X-ray spectroscopy. The results showed that the synthesized products display the crystalline structure and vibration modes of hydroxyapatite. Transmission electron micrograph revealed that nanohydroxyapatite exhibits elongated rod morphology with large aspect ratios. Nanohydroxyapatite prepared from a surfactant of 1.25 millimole showed good thermal stability at 1000 °C on the basis of thermogravimetric analysis. Simulated body fluid immersion test indicated that an apatite layer can be readily deposited on the nanohydroxyapatite surface demonstrating its good bio-resorbability. Copyright © 2011 American Scientific Publishers All rights reserved.

Research Area(s)

  • Biocompatibility, Hydrothermal treatment, Hydroxyapatite nanorod, Thermal stability