Highly sensitive fluorescent probe for thiols based on combination of PET and ESIPT mechanisms

Minhuan Lan; Jiasheng Wu; Weimin Liu; Hongyan Zhang; Wenjun Zhang; Xiaoqing Zhuang; Pengfei Wang

doi:10.1016/j.snb.2011.04.042

Highly sensitive fluorescent probe for thiols based on combination of PET and ESIPT mechanisms

Minhuan Lan, Jiasheng Wu, Weimin Liu, Hongyan Zhang, Wenjun Zhang^*, Xiaoqing Zhuang, Pengfei Wang^*

^*Corresponding author for this work

Centre of Super-Diamond and Advanced Films

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

86 Citations (Scopus)

Abstract

We have developed a conceptually new design strategy for fluorescent probes based on a combinational use of photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT) mechanisms. This turn-on fluorescence thiol-probe shows fast responses to mercapto-biomolecules with high sensitivity and selectivity. Furthermore, it was used for imaging in living cells with excellent performance. © 2011 Elsevier B.V.

Original language	English
Pages (from-to)	332-337
Journal	Sensors and Actuators, B: Chemical
Volume	156
Issue number	1
DOIs	https://doi.org/10.1016/j.snb.2011.04.042
Publication status	Published - 10 Aug 2011

Research Keywords

3-Hydroxyflavone derivative
ESIPT
Fluorescent probe
PET
Thiol probe

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title = "Highly sensitive fluorescent probe for thiols based on combination of PET and ESIPT mechanisms",

abstract = "We have developed a conceptually new design strategy for fluorescent probes based on a combinational use of photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT) mechanisms. This turn-on fluorescence thiol-probe shows fast responses to mercapto-biomolecules with high sensitivity and selectivity. Furthermore, it was used for imaging in living cells with excellent performance. {\textcopyright} 2011 Elsevier B.V.",

keywords = "3-Hydroxyflavone derivative, ESIPT, Fluorescent probe, PET, Thiol probe",

author = "Minhuan Lan and Jiasheng Wu and Weimin Liu and Hongyan Zhang and Wenjun Zhang and Xiaoqing Zhuang and Pengfei Wang",

year = "2011",

month = aug,

day = "10",

doi = "10.1016/j.snb.2011.04.042",

language = "English",

volume = "156",

pages = "332--337",

journal = "Sensors and Actuators, B: Chemical",

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TY - JOUR

T1 - Highly sensitive fluorescent probe for thiols based on combination of PET and ESIPT mechanisms

AU - Lan, Minhuan

AU - Wu, Jiasheng

AU - Liu, Weimin

AU - Zhang, Hongyan

AU - Zhang, Wenjun

AU - Zhuang, Xiaoqing

AU - Wang, Pengfei

PY - 2011/8/10

Y1 - 2011/8/10

N2 - We have developed a conceptually new design strategy for fluorescent probes based on a combinational use of photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT) mechanisms. This turn-on fluorescence thiol-probe shows fast responses to mercapto-biomolecules with high sensitivity and selectivity. Furthermore, it was used for imaging in living cells with excellent performance. © 2011 Elsevier B.V.

AB - We have developed a conceptually new design strategy for fluorescent probes based on a combinational use of photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT) mechanisms. This turn-on fluorescence thiol-probe shows fast responses to mercapto-biomolecules with high sensitivity and selectivity. Furthermore, it was used for imaging in living cells with excellent performance. © 2011 Elsevier B.V.

KW - 3-Hydroxyflavone derivative

KW - ESIPT

KW - Fluorescent probe

KW - PET

KW - Thiol probe

UR - http://www.scopus.com/inward/record.url?scp=79957820947&partnerID=8YFLogxK

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-79957820947&origin=recordpage

U2 - 10.1016/j.snb.2011.04.042

DO - 10.1016/j.snb.2011.04.042

M3 - RGC 21 - Publication in refereed journal

SN - 0925-4005

VL - 156

SP - 332

EP - 337

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

IS - 1

ER -

Highly sensitive fluorescent probe for thiols based on combination of PET and ESIPT mechanisms

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