Highly Selective and Efficient Ring Hydroxylation of Alkylbenzenes with Hydrogen Peroxide and an Osmium(VI) Nitrido Catalyst
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
---|---|
Pages (from-to) | 12260-12263 |
Journal / Publication | Angewandte Chemie - International Edition |
Volume | 56 |
Issue number | 40 |
Online published | 23 Aug 2017 |
Publication status | Published - 25 Sept 2017 |
Link(s)
Abstract
The OsVI nitrido complex, OsVI(N)(quin)2(OTs) (1, quin=2-quinaldinate, OTs=tosylate), is a highly selective and efficient catalyst for the ring hydroxylation of alkylbenzenes with H2O2 at room temperature. Oxidation of various alkylbenzenes occurs with ring/chain oxidation ratios ranging from 96.7/3.3 to 99.9/0.1, and total product yields from 93 % to 98 %. Moreover, turnover numbers up to 6360, 5670, and 3880 can be achieved for the oxidation of p-xylene, ethylbenzene, and mesitylene, respectively. Density functional theory calculations suggest that the active intermediate is an OsVIII nitrido oxo species.
Research Area(s)
- alkylbenzenes, hydrogen peroxide, hydroxylation, nitrido, osmium complexes
Citation Format(s)
Highly Selective and Efficient Ring Hydroxylation of Alkylbenzenes with Hydrogen Peroxide and an Osmium(VI) Nitrido Catalyst. / Kwong, Hoi-Ki; Lo, Po-Kam; Yiu, Shek-Man et al.
In: Angewandte Chemie - International Edition, Vol. 56, No. 40, 25.09.2017, p. 12260-12263.
In: Angewandte Chemie - International Edition, Vol. 56, No. 40, 25.09.2017, p. 12260-12263.
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review