High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM)

Andy K. S. Lau; Bob M. F. Chung; Anson H. L. Tang; Pan Yeung; Xiaoming Wei; Barbara P. Chan; Kenneth K. Y. Wong; H. C. Shum; Kevin K. Tsia

doi:10.1109/IPCon.2015.7323567

High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM)

Andy K. S. Lau^*, Bob M. F. Chung, Anson H. L. Tang, Pan Yeung, Xiaoming Wei, Barbara P. Chan, Kenneth K. Y. Wong, H. C. Shum, Kevin K. Tsia

^*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

We demonstrate quantitative-phase asymmetric-detection time-stretch optical microscopy (Q-ATOM) for ultra-high-throughput label-free image-based single-cell classification and phenotyping at an ultrafast imaging line-scan rate of 11.6 MHz (∼120,000 cells/sec). © 2015 IEEE.

Original language	English
Title of host publication	2015 IEEE Photonics Conference (IPC)
Publisher	IEEE
Pages	5-6
ISBN (Electronic)	978-1-4799-7465-8
DOIs	https://doi.org/10.1109/IPCon.2015.7323567
Publication status	Published - 2015
Externally published	Yes
Event	IEEE Photonics Conference, IPC 2015 - Reston, United States Duration: 30 Aug 2015 → 31 Aug 2015

Publication series

Name	IEEE Photonics Conference, IPC

Conference

Conference	IEEE Photonics Conference, IPC 2015
Place	United States
City	Reston
Period	30/08/15 → 31/08/15

Funding

This work is partially supported by grants from the Research Grants Council of Hong Kong Special Administrative Region, China (HKU 717911E, HKU 720112E, HKU717212E, 17207714), and ITS/090114the University Development Fund of HKU.

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10.1109/IPCon.2015.7323567

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Lau, A. K. S., Chung, B. M. F., Tang, A. H. L., Yeung, P., Wei, X., Chan, B. P., Wong, K. K. Y., Shum, H. C., & Tsia, K. K. (2015). High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM). In 2015 IEEE Photonics Conference (IPC) (pp. 5-6). Article 7323567 (IEEE Photonics Conference, IPC). IEEE. https://doi.org/10.1109/IPCon.2015.7323567

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title = "High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM)",

abstract = "We demonstrate quantitative-phase asymmetric-detection time-stretch optical microscopy (Q-ATOM) for ultra-high-throughput label-free image-based single-cell classification and phenotyping at an ultrafast imaging line-scan rate of 11.6 MHz (∼120,000 cells/sec). {\textcopyright} 2015 IEEE.",

author = "Lau, {Andy K. S.} and Chung, {Bob M. F.} and Tang, {Anson H. L.} and Pan Yeung and Xiaoming Wei and Chan, {Barbara P.} and Wong, {Kenneth K. Y.} and Shum, {H. C.} and Tsia, {Kevin K.}",

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year = "2015",

doi = "10.1109/IPCon.2015.7323567",

language = "English",

series = "IEEE Photonics Conference, IPC",

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Lau, AKS, Chung, BMF, Tang, AHL, Yeung, P, Wei, X, Chan, BP, Wong, KKY, Shum, HC & Tsia, KK 2015, High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM). in 2015 IEEE Photonics Conference (IPC)., 7323567, IEEE Photonics Conference, IPC, IEEE, pp. 5-6, IEEE Photonics Conference, IPC 2015, Reston, United States, 30/08/15. https://doi.org/10.1109/IPCon.2015.7323567

High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM). / Lau, Andy K. S.; Chung, Bob M. F.; Tang, Anson H. L. et al.
2015 IEEE Photonics Conference (IPC). IEEE, 2015. p. 5-6 7323567 (IEEE Photonics Conference, IPC).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

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AU - Lau, Andy K. S.

AU - Chung, Bob M. F.

AU - Tang, Anson H. L.

AU - Yeung, Pan

AU - Wei, Xiaoming

AU - Chan, Barbara P.

AU - Wong, Kenneth K. Y.

AU - Shum, H. C.

AU - Tsia, Kevin K.

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AB - We demonstrate quantitative-phase asymmetric-detection time-stretch optical microscopy (Q-ATOM) for ultra-high-throughput label-free image-based single-cell classification and phenotyping at an ultrafast imaging line-scan rate of 11.6 MHz (∼120,000 cells/sec). © 2015 IEEE.

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High-throughput intrinsic single-cell phenotyping by quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM)

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