High sensitive DNA detection amplified by enlarging Au-nanoparticles in situ

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)328-329
Journal / PublicationChemistry Letters
Issue number3
Publication statusPublished - 5 Mar 2002
Externally publishedYes

Abstract

A new approach to amplify the micogravimetric quartz crystal microbalance (QCM) assay of DNA by enlarging Au-nanoparticles in situ has been reported. To avoid the interference of the non-specific enlargement effect mercaptoethanol was served as blocking reagent. The results show that the sensitivity of detecting DNA is remarkably increased to ca. 1 × 10-15 M.

Citation Format(s)

High sensitive DNA detection amplified by enlarging Au-nanoparticles in situ. / Ma, Zhanfang; Li, Jinru; Jiang, Long et al.
In: Chemistry Letters, No. 3, 05.03.2002, p. 328-329.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review