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High sensitive DNA detection amplified by enlarging Au-nanoparticles in situ

  • Zhanfang Ma
  • , Jinru Li
  • , Long Jiang
  • , Mengsu Yang
  • , Sen-fang Sui

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

A new approach to amplify the micogravimetric quartz crystal microbalance (QCM) assay of DNA by enlarging Au-nanoparticles in situ has been reported. To avoid the interference of the non-specific enlargement effect mercaptoethanol was served as blocking reagent. The results show that the sensitivity of detecting DNA is remarkably increased to ca. 1 × 10-15 M.
Original languageEnglish
Pages (from-to)328-329
JournalChemistry Letters
Issue number3
DOIs
Publication statusPublished - 5 Mar 2002
Externally publishedYes

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